Category Archives: Determinants of Health
The relationship between minority stress and biological outcomes: A systematic review
Sexual minority (non-heterosexual) individuals experience higher rates of physical health problems. Minority stress has been the primary explanatory model to account for this disparity. The purpose of this study was...
Household-focused interventions to enhance the treatment and management of HIV in low- and middle-income countries: A scoping review
BACKGROUND: HIV remains a major public health challenge in many low- and middle-income countries (LMICs). The initiation of a greater number of people living with HIV (PLHIV) onto antiretroviral therapy...
A client-centered relational framework on barriers to the integration of HIV and substance use services: A systematic review
BACKGROUND: Given the close connection between human immunodeficiency virus (HIV) infection and substance use disorder (SUD), access to integrated HIV and SUD services is critical for individuals experiencing both challenges...
Factors associated with antiretroviral therapy adherence in adults: An integrative review of literature
AIDS is an advanced clinical manifestation of HIV infection. It generates severe immunodeficiency and associated infections that may lead to death. The antiretroviral therapy (ART) has reduced the morbimortality of...
Different transmission routes and the risk of advanced HIV disease: A systematic review and network meta-analysis of observational studies
Background: A substantial proportion of people living with HIV (PLHIV) present for care with advanced HIV disease (AHD), which may result in difficulty reaching the “90-90-90” target to end AIDS...
Stigma reduction interventions in people living with HIV to improve health-related quality of life
As the UNAIDS 90-90-90 targets for people living with HIV are increasingly being reached in many contexts, health-related quality of life, the so-called fourth 90, warrants special attention. HIV-related stigma...
Factors associated with general sexual functioning and sexual satisfaction among people living with HIV: A systematic review
Sexual difficulties, experienced by half of the people living with HIV (PLWH), not only affect quality of life but have been associated with lower adherence to antiretroviral medication. This systematic...
HIV testing barriers and intervention strategies among men, transgender women, female sex workers and incarcerated persons in the Caribbean: A systematic review
BACKGROUND: This systematic review summarises evidence on the HIV testing barriers and intervention strategies among Caribbean populations and provides pertinent implications for future research endeavours designed to increase rates of...
Which HIV-infected youth are at risk of developing depression and what treatments help? A systematic review focusing on Southern Africa
Background Depression is common in people with HIV and is associated with lower quality of life, reduced medication adherence, worse disease progression and higher risk of transmission to others. While...
Adherence to HIV post-exposure prophylaxis for children/adolescents who have been sexually assaulted: A systematic review of barriers, enablers, and interventions
Post-exposure prophylaxis (PEP) is a key intervention for preventing HIV acquisition, including following sexual assault. However, uptake and completion rates for HIV PEP are lowest following sexual assault, with only...
Barriers and facilitators to the successful transition of adolescents living with HIV from pediatric to adult care in low and middle-income countries: A systematic review and policy analysis
The purpose of this systematic review was twofold. First, we sought to summarize the literature on barriers and facilitators to successful healthcare transition for adolescents living with HIV from low-...
