Category Archives: Determinants of Health
Treatment of syphilis in HIV-infected subjects: A systematic review of the literature
Background: The optimal antimicrobial regimen to treat syphilis in HIV-infected subjects remains controversial. Objective To systematically assess the literature for studies evaluating syphilis treatment regimens in this population. Methods: Two...
The paradigm of universal access to HIV-treatment and human rights violation: How do we treat HIV-positive people who use drugs?
HIV-positive people who use drugs (PWUDs) are particularly vulnerable for suboptimal access to highly active antiretroviral therapy (HAART). We conducted a systematic review to identify factors associated with suboptimal HAART...
Barriers to access to antiretroviral treatment in developing countries: A review
OBJECTIVE: To present a review of barriers impeding people living with HIV/AIDS in developing countries from accessing treatment, and to make recommendations for further studies. METHODS: Electronic databases, websites of...
Complementary and alternative medicine use among HIV-positive people: Research synthesis and implications for HIV care
Use of complementary and alternative medicine (CAM) is prevalent among HIV-positive individuals despite the success of antiretroviral treatments and limited evidence of CAM’s safety and efficacy. To characterize the potential...
Mental health and resilience in HIV/AIDS-affected children: A review of the literature and recommendations for future research
BACKGROUND: To date, research on mental health in HIV-affected children (children who have an HIV-positive caregiver or live with the virus themselves) has focused on risk factors associated with the...
Cancer and the ‘other’ noncommunicable chronic diseases in older people living with HIV/AIDS in resource-limited settings: A challenge to success
Objective: There is considerable research around the morbidity and mortality related to noncommunicable diseases (NCDs), particularly cardiovascular disease and diabetes, among people living with HIV/AIDS (PLWHA) in resource-richer settings. Less...
Improved access to early infant diagnosis is a critical part of a child-centric prevention of mother-to-child transmission agenda
BACKGROUND: Prevention-of-mother-to-child-transmission (PMTCT) programs have made it possible to achieve dramatic reductions in the rate of vertical HIV transmission. However, high attrition, particularly after delivery, has limited the impact of...
Mental health of HIV-seropositive women during pregnancy and postpartum period: A comprehensive literature review
With growing numbers of HIV-seropositive (HIV+) women of child-bearing age and increased access to effective clinical protocols for preventing mother-to-child transmission (MTCT) of HIV, mental health-related factors have become increasingly...
A systematic review of interventions to reduce HIV-related stigma and discrimination from 2002 to 2013: How far have we come?
Introduction: HIV-related stigma and discrimination continue to hamper efforts to prevent new infections and engage people in HIV treatment, care and support programmes. The identification of effective interventions to reduce...
Neurodevelopment in children born to HIV-infected mothers by infection and treatment status
BACKGROUND: We reviewed the impact of HIV, HIV exposure, and antiretroviral therapy/prophylaxis on neurodevelopmental outcomes of HIV-infected and HIV-exposed-uninfected infants and children. METHODS: A literature search of Medline, Embase, PsychINFO,...
