Category Archives: Epidemiology and Determinants of Health
Use of the multiplier method to estimate the size of populations most at risk of human immunodeficiency virus infection in China: A systematic review
OBJECTIVE: United Nations Programme on human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome and World Health Organization believe that some of the benchmark numbers collected may be inaccurate when using the multiplier...
Informing the measurement of wellbeing among young people living with HIV in sub-Saharan Africa for policy evaluations: A mixed-methods systematic review
Young people living with HIV (YPLHIV) in sub-Saharan Africa (SSA) are at high risk of having a poor quality of life. Addressing wellbeing explicitly within HIV/AIDS policies could assist mitigation...
Burden of Talaromyces marneffei infection in people living with HIV/AIDS in Asia during ART era: A systematic review and meta-analysis
BACKGROUND: Talaromyces marneffei (TM) is a dimorphic fungus mainly prevalent in Southeast Asian countries, which often causes disseminated life-threatening infection. TM infection often occurs in HIV/AIDS patients even in the...
Cryptococcal antigenemia and its predictors among HIV infected patients in resource limited settings: A systematic review
BACKGROUND: Cryptococcosis is an opportunistic fungal infection that primarily affects people with advanced HIV/AIDS and is an important cause of morbidity and mortality around the globe. By far the most...
A systematic review and meta-analysis to assess the association between urogenital schistosomiasis and HIV/AIDS infection
BACKGROUND: Urogenital schistosomiasis and HIV/AIDS infections are widespread in sub-Saharan Africa (SSA) leading to substantial morbidity and mortality. The co-occurrence of both diseases has led to the possible hypothesis that...
The prevalence of cryptococcal antigen (CrAg) and benefits of pre-emptive antifungal treatment among HIV-infected persons with CD4+ T-cell counts < 200 cells/muL: Evidence based on a meta-analysis
BACKGROUND: Current WHO guidelines (2018) recommend screening for cryptococcal antigen (CrAg) in HIV-infected persons with CD4+ T cell counts< 100 cells/muL, followed by pre-emptive antifungal therapy among CrAg positive (CrAg+)...
Prevalence of sexually transmitted infections and human immunodeficiency virus in transgender persons: A systematic review
Purpose: Despite reportedly high rates of human immunodeficiency virus (HIV) and other sexually transmitted infections (STIs) among transgender people, laboratory-proven prevalence of these infections in this population has not been...
Cryptococcal meningitis: A review of cryptococcal antigen screening programs in Africa
INTRODUCTION: Cryptococcal meningitis remains a significant contributor to AIDS-related mortality despite widened access to antiretroviral therapy. Cryptococcal antigen (CrAg) can be detected in the blood prior to development of meningitis....
Screening algorithms to reduce burden of pediatric HIV testing: A systematic review and meta-analysis
BACKGROUND: The accuracy of symptom screening to identify children eligible for further HIV testing in generalized epidemics has been examined in several studies. We performed a systematic review and meta-analysis...
Unknown HIV status and the TB/HIV collaborative control program in Ethiopia: Systematic review and meta-analysis
BACKGROUND: Ethiopia has shown significant efforts to address the burden of TB/HIV comorbidity through the TB/HIV collaborative program. However, these diseases are still the highest cause of death in the...
