Category Archives: Epidemiology and Determinants of Health

Stigma and intersectionality: A systematic review of systematic reviews across HIV/AIDS, mental illness, and physical disability

2018

BACKGROUND: Stigma across HIV/AIDS, mental illness, and physical disability can be co-occurring and may interact with other forms of stigma related to social identities like race, gender, and sexuality. Stigma...

Improving PrEP implementation through multilevel interventions: A synthesis of the literature

2018

There are many challenges to accessing PrEP and thus low uptake in the United States. This review (2007-2017) of PrEP implementation identified barriers to PrEP and interventions to match those...

Associations between highly active antiretroviral therapy and the presence of HPV, premalignant and malignant cervical lesions in sub-Saharan Africa, a systematic review: Current evidence and directions for future research

2017

OBJECTIVES: In sub-Saharan Africa, substantial international funding along with evidence-based clinical practice have resulted in an unparalleled scale-up of access to antiretroviral treatment at a higher CD4 count. The role...

A meta-analysis of effectiveness of interventions to improve adherence in pregnant women receiving antiretroviral therapy in sub-Saharan Africa

2018

OBJECTIVE: We evaluated the effectiveness of interventions aimed at improving antiretroviral therapy (ART) adherence during pregnancy in sub-Saharan Africa. METHODS: For this meta-analysis, the following databases were searched: MEDLINE Complete,...

A systematic review of the current status of safer conception strategies for HIV affected heterosexual couples in Sub-Saharan Africa

2018

We conducted a systematic review of safer conception strategies (SCS) for HIV-affected couples in sub-Saharan Africa to inform evidence-based safer conception interventions. Following PRISMA guidelines, we searched fifteen electronic databases...

Economic strengthening for HIV testing and linkage to care: A review of the evidence

2018

Delayed HIV diagnosis and enrollment in HIV care can lead to negative health outcomes for individuals and pose major barriers to achieving the UNAIDS 90-90-90 treatment targets. Household economic strengthening...

Statin use and all-cause mortality in people living with HIV: A systematic review and meta-analysis

2018

BACKGROUND: It is unknown whether statin use among people living with HIV results in a reduction in all-cause mortality. We aimed to evaluate the effect of statin use on all-cause...

Evaluating the effectiveness of sexual and reproductive health services during humanitarian crises: A systematic review

2018

BACKGROUND: An estimated 32 million women and girls of reproductive age living in emergency situations, all of whom require sexual and reproductive health (SRH) information and services. This systematic review...

Increased risk of aminoglycoside-induced hearing loss in MDR-TB patients with HIV coinfection

2018

SETTING: A high proportion of individuals with multidrug-resistant tuberculosis (MDR-TB) develop permanent hearing loss due to ototoxicity caused by injectable aminoglycosides (AGs). The prevalence of AG-induced hearing loss is greatest...

Global burden of atherosclerotic cardiovascular disease in people living with the human immunodeficiency virus: A systematic review and meta-analysis

2018

Background -With advances in anti-retroviral therapy, most deaths in people with human immune-deficiency virus (HIV) are now due to non-communicable illnesses especially cardiovascular disease. We determine the association between HIV...

Predictors of human immunodeficiency virus (HIV) infection in primary care among adults living in developed countries: A systematic review

2018

BACKGROUND: Early diagnosis of human immunodeficiency virus (HIV) is important because antiretroviral therapies are more effective if infected individuals are diagnosed early. Diagnosis of HIV relies on laboratory testing and...

Noncommunicable diseases among HIV-infected persons in low-income and middle-income countries: A systematic review and meta-analysis

2018

OBJECTIVE: To appropriately identify and treat noncommunicable diseases (NCDs) among persons living with HIV (PLHIV) in low-and-middle-income countries (LMICs), it is imperative to understand the burden of NCDs among PLHIV...

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