Category Archives: Epidemiology and Determinants of Health
Effectiveness of digital health interventions on antiretroviral therapy adherence among people living with HIV in India: A systematic review with an RCT-only meta-analysis
The widespread use of combination antiretroviral therapy has transformed HIV infection into a chronic condition, with life expectancy of people with HIV (PWH) approaching that of the general population when...
Prevalence and risk factors for oropharyngeal, esophageal, and oral candidiasis in HIV-positive individuals: A systematic review and meta-analysis
Background: Oral, oropharyngeal, and esophageal candidiasis are common forms of mucosal candidiasis (MC) in people living with human immunodeficiency virus/acquired immunodeficiency syndrome (PLWHA). Despite differences in infection sites, oral, oropharyngeal, and...
The benefit of physical exercise in improving quality of life, VO(2) max and sleep quality among older adults living with HIV: A systematic review and meta-analysis
Background: Older adults living with HIV face multiple health challenges, yet evidence on the impact of exercise on their well-being remains limited. Regular physical activity is known to have multiple benefits...
Integrated service delivery models for triple elimination of mother to child transmission of human immunodeficiency virus, syphilis, and hepatitis B virus: A global systematic review and meta-analysis
BACKGROUND AND OBJECTIVES: Despite global commitment to the World Health Organization triple elimination initiative, evidence on integrated antenatal service delivery models that simultaneously address human immunodeficiency virus (HIV), syphilis, and...
Perspective of people living with HIV and healthcare workers on the uptake, barriers, and benefits of multimonth dispensing: A qualitative systematic review
INTRODUCTION: Multimonth dispensing (MMD) is a strategy in the HIV care continuum for people living with HIV (PLWH), especially for those who are virally suppressed. With the increase in MMD...
Simulation modeling for the design and evaluation of HIV drug resistance interventions: A systematic review of literature
Background The utility of antiretroviral therapy (ART) in the management of human immunodeficiency virus (HIV) is being challenged by growing HIV drug resistance (HIVDR). Although simulation modelling is useful for...
Integration of HIV, Hepatitis B, and C, and sexually transmitted infections services: A scoping review of the benefits and challenges
BACKGROUND: Integrating clinical programs and services is a cost-effective approach that can improve health and system outcomes. This review aimed to provide an overview of the benefits and challenges of...
Interventions to improve access to sexual and reproductive health services for adolescents living with HIV in sub-Saharan Africa: A scoping review
OBJECTIVE: Adolescents living with HIV (ALHIV) face barriers to accessing sexual and reproductive health (SRH) services, negatively affecting their health and quality of life. These challenges are particularly pronounced in...
Prevalence and risk factors for cytomegalovirus retinitis among people living with HIV in sub-Saharan Africa in the antiretroviral therapy era: A systematic review and meta-analysis
Cytomegalovirus retinitis has remained an alarming and potentially vision-threatening opportunistic disease in the population living with HIV, especially in cases of extreme immunosuppression. Although the introduction of antiretroviral therapy has...
Exploring the potential of cognitive intra-individual variability in HIV care and research in adults with HIV: A concept analysis
Cognitive intraindividual variability (IIV) refers to the variability in one’s ability to sustain consistent cognitive performance. This phenomenon is linked to the emergence of cognitive impairment and dementia. The aim...
Effectiveness of digital health interventions for improving antiretroviral therapy outcomes in people with HIV: Meta-analysis and trial sequential analysis of randomized controlled trials
Background: Digital health interventions (DHIs) are increasingly used to support antiretroviral therapy (ART) management among people living with HIV. However, existing systematic reviews have largely focused on single intervention types or...
The burden of HIV-related stigma on clinical and quality of life outcomes: results from a systematic literature review
BACKGROUND: HIV-related stigma adversely impacts people with HIV. As part of a systematic literature review (SLR) to evaluate 6 research questions on HIV-related stigma among people with HIV, data from...
