Category Archives: Epidemiology and Determinants of Health
Barriers and facilitators influencing PrEP uptake among men who have sex with men and transgender women in the United States: A systematic review
In the United States, men who have sex with men (MSM) and transgender women (TGW) have high HIV pre-exposure prophylaxis (PrEP) awareness, yet uptake rates remain extremely low. This signifies...
Incidence and predictors of loss to follow-up among adults on antiretroviral therapy in Ethiopia: A systematic review and meta-analysis of cohort studies
Background Loss to follow-up (LTFU) from antiretroviral therapy (ART) remains a major public health concern worldwide, including in Ethiopia. However, nationally representative pooled cohort data on LTFU among adults receiving...
Youth advisory board engagement in HIV research in low- and middle-income countries: A scoping review and additional youth perspectives
Background. Engaging young people (10–24 years old) in research has been shown to improve the uptake and impact of HIV interventions in youth. However, how youth are engaged in Youth...
Surveillance of HIV-1 drug resistance in Tanzania across the pre- and post-dolutegravir eras: A systematic review and meta-analysis
This systematic review and meta-analysis assessed the prevalence, mutation patterns, and factors associated with HIV drug resistance (HIVDR) in Tanzania. We searched PubMed/MEDLINE and Embase from January 1, 2006, to...
Global Perspectives on Pre-Exposure Prophylaxis: A Systematic Review and Meta-Analysis of Health Care Providers’ Awareness, Willingness, and Barriers
This systematic review and meta-analysis aimed to assess health care providers’ awareness, willingness, and key barriers in implementing HIV pre-exposure prophylaxis (PrEP). The review followed the Preferred Reporting Items for...
Prevalence of oral high-risk HPV and HPV16 infection among people living with HIV: A systematic review and meta-analysis
Objectives: Little is known about the natural history of oral HPV in people living with HIV (PLWH). This systematic review and meta-analysis evaluated oral HPV prevalence among PLWH. Methods: Studies with ≥18-year-old...
Prevalence and associated factors of ICD/DSM-diagnosed depressive disorders among people living with HIV: A systematic review and meta-analysis
Background: Depressive disorders are highly prevalent among people living with HIV (PLWH), severely impairing quality of life and antiretroviral therapy (ART) adherence. While ART advances call for reassessing depressive disorders among...
A web of risk: Multilevel factors and feedback loops (re)produce HIV ‘risk’ among gay, bisexual and other men who have sex with men—A global systematic review
BACKGROUND: HIV literature shows that gay, bisexual and men who have sex with other men (GBMSM) experience inequities across social and contextual factors. Given growing inequities, this study used complex...
The burden of sarcopenia in people living with HIV: A systematic review and meta-analysis across WHO regions
BACKGROUND: Sarcopenia, characterized by progressive loss of skeletal muscle mass and function, represents an underrecognized comorbidity in people living with human immunodeficiency virus, and comprehensive prevalence data across WHO regions...
Informed consent in molecular HIV epidemiology: A rapid review of the literature to identify concerns and recommendations
In the United States, molecular HIV epidemiology (MHE) is a key part of the National HIV/AIDS Strategy, which incorporates the evaluation of HIV genetic sequences for cluster detection and response....
Prevalence of HIV-associated nephropathy in children: A systematic review with meta-analysis of studies published between 2004 and 2019
Introduction Despite major advances in antiretroviral therapy, HIV infection remains a significant global public health challenge. HIV can directly affect the kidneys, leading to HIV-associated nephropathy in children, a condition...
HIV mortality surveillance in Nigeria, a systematic review of trends, determinants, and implications for public health policy
Despite substantial progress in expanding antiretroviral therapy (ART) coverage and scaling up prevention interventions, Human Immunodeficiency Virus (HIV) related mortality remains a significant public health challenge in several high-burden settings,...
