Category Archives: Epidemiology and Determinants of Health

Secrets and safety in the age of AIDS: Does HIV disclosure lead to safer sex?

2004

To fuel the HIV/AIDS epidemic, HIV-seropositive individuals must interact unsafely with HIV-seronegative individuals. Research indicates that up to one third of individuals diagnosed with HIV continue to have unprotected sex,...

Adherence to highly active antiretroviral therapy in Spain: A meta-analysis

2011

OBJECTIVES: To estimate the percentage of adherence to highly-active antiretroviral therapy (HAART) in Spanish observational studies and to identify the variables associated with adherence. METHODS: Seven electronic databases were used...

A systematic review of delay in the diagnosis and treatment of tuberculosis

2008

BACKGROUND: Early diagnosis and immediate initiation of treatment are essential for an effective tuberculosis (TB) control program. Delay in diagnosis is significant to both disease prognosis at the individual level...

Socio-demographic characteristics and behavioral risk factors of female sex workers in sub-saharan Africa: A systematic review

2012

Sex work remains an important contributor to HIV transmission within early, advanced and regressing epidemics in sub-Saharan Africa, but its social and behavioral underpinnings remain poorly understood, limiting the impact...

No relationship between TNF-alpha genetic variants and combination antiretroviral therapy-related lipodystrophy syndrome in HIV type 1-infected patients: A case-control study and a meta-analysis

2011

Tumor necrosis factor alpha (TNF-alpha) is thought to be involved in the pathogenic and metabolic events associated with HIV-1 infection. We assessed whether carriage of the TNF-alpha gene promoter single...

Bacterial vaginosis and HIV acquisition: A meta-analysis of published studies

2008

OBJECTIVES: To assess and summarize the published literature on the extent to which bacterial vaginosis may increase the risk of HIV acquisition. DESIGN: Meta-analysis of published studies. METHODS: Medline and...

Integration of HIV/AIDS services with maternal, neonatal and child health, nutrition, and family planning services

2012

Background: The integration of HIV/AIDS and maternal, neonatal, child health and nutrition services (MNCHN), including family planning (FP) is recognized as a key strategy to reduce maternal and child mortality...

Accuracy of serological assays for detection of recent infection with HIV and estimation of population incidence: A systematic review

2009

We systematically reviewed the accuracy of serological tests for recent infections with HIV that have become widely used for measuring population patterns incidence of HIV. Across 13 different assays, sensitivity...

Global epidemiology of injecting drug use and HIV among people who inject drugs: A systematic review

2008

Background: Injecting drug use is an increasingly important cause of HIV transmission in most countries worldwide. Our aim was to determine the prevalence of injecting drug use among individuals aged...

CD4+ guided antiretroviral treatment interruption in HIV infection: A meta-analysis

2008

The aim of this meta-analysis study was to evaluate the relative risk of death or AIDS-defining events associated to CD4+ guided treatment interruption in patients with chronic HIV infection. A...

HIV status in discordant couples in sub-Saharan Africa: A systematic review and meta-analysis

2010

BACKGROUND: Most couples affected by HIV/AIDS in sub-Saharan Africa live in discordant relationships. Men are thought to be the index case in most relationships, and most social marketing and awareness...

Towards universal voluntary HIV testing and counselling: A systematic review and meta-analysis of community-based approaches

2013

BACKGROUND: Effective national and global HIV responses require a significant expansion of HIV testing and counselling (HTC) to expand access to prevention and care. Facility-based HTC, while essential, is unlikely...

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