Category Archives: Epidemiology and Determinants of Health

The mother-to-child transmission of HIV-1 and profile of viral reservoirs in pediatric population: A systematic review with meta-analysis of the Cameroonian studies

2023

Background: The mother-to-child transmission of HIV-1 (MTCT) remains on the major route of HIV-transmission among pediatric populations in Africa. Though a prevention of MTCT (PMTCT) high-priority country, data on the MTCT...

A qualitative systematic literature review of the role of U.S. pharmacists in prescribing pre-exposure prophylaxis (PrEP)

2023

Pre-Exposure Prophylaxis (PrEP) is an effective treatment to combat the human immunodeficiency virus (HIV) endemic, but the uptake of PrEP has been low in the United States (U.S.). While individuals...

Universal health coverage for antiretroviral treatment: A review

2023

Universal health coverage is essential for the progress to end threats of the acquired immunodeficiency syndrome epidemic. The current review assesses the publication rate, strategies and barriers for antiretroviral therapy...

Virological failure and adherence to antiretroviral therapy in adolescents and young adults living with human immunodeficiency virus

2023

Objective: HIV (human immunodeficiency virus) infection remains a major public health challenge. Infected young people at any age are less likely to adhere to care in a timely manner and to...

Prevalence and characteristics of nonalcoholic fatty liver disease and fibrosis in people living with HIV monoinfection: A systematic review and meta-analysis

2023

Background and Aims Liver disease remains a leading cause of morbidity and mortality among people living with HIV (PLWH). Emerging data have shown that PLWH are at high risk for...

The prevalence of HIV-infected patients with virological suppression but a CD4+ T-cell count of ≤ 200 cells/mm3 after highly active antiretroviral therapy initiation: A meta-analysis

2022

Highly active antiretroviral therapy (HAART) strongly inhibits HIV replication. However, many patients show suboptimal immune recovery (SIR), as defined by virological suppression (i.e. low viral load) with a CD4+ T-cell count...

A systematic review and meta-analysis to estimate the time from HIV infection to diagnosis for people with HIV

2022

Timely HIV diagnosis is critical to minimizing transmission events. We sought to estimate the meantime from HIV infection to diagnosis and its temporal trend among people with HIV. Following Preferred...

So many harms, so little benefit: A global review of the history and harms of HIV criminalisation

2023

Since the early years of HIV, many jurisdictions have criminalised HIV non-disclosure, potential or perceived exposure, and transmission. Many of these laws and prosecutions are without a scientific basis and...

Perinatal outcomes associated with combination antiretroviral therapy compared with monotherapy

2023

Objectives: Increasing numbers of women living with HIV (WLHIV) worldwide receive combination antiretroviral therapy (cART) during pregnancy. We aimed to assess the risk of adverse perinatal outcomes in pregnant WLHIV receiving...

Toxoplasma gondii infection in immunocompromised patients in Iran (2013–2022): A systematic review and meta-analysis

2022

BACKGROUND: Toxoplasma gondii infection (toxoplasmosis) has the potential to cause a serious disease in immunocompromised patients and can be fatal in this population. We conducted a systematic review and meta-analysis...

Cost-effective strategies of testing for HIV and sexually transmitted infections (STIs)

2022

Rates of chlamydia, gonorrhea, and infectious syphilis have risen in Canada from 2015 to 2019. An observed decrease in HIV cases has been detected recently, however a reduction in testing...

What is polypharmacy in people living with HIV/AIDS? A systematic review

2022

Polypharmacy in people living with HIV/AIDS (PLWHA) is a rising morbidity that exacts hefty economic burden on health budgets in addition to other adverse clinical outcomes. Despite recent advances, uncertainty...

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