Category Archives: Epidemiology and Determinants of Health
Global prevalence and associated clinical markers of thrombocytopenia in people living with HIV: Evidence from meta-analysis
Thrombocytopenia is one of the complications in human immunodeficiency virus (HIV) patients. To improve the health outcomes of patients living with HIV, it is important to understand the prevalence and...
Efficacy, safety, and tolerability of isoniazid preventive therapy for tuberculosis in people living with HIV
Objective: The aim of this study was to systematically assess the efficacy, safety, and tolerability of isoniazid preventive therapy (IPT) for tuberculosis (TB) in people with HIV (PWH). Design: A systematic review...
A systematic review of four decades of prevalence of oral soft tissue infections and conditions among adult HIV patients in India
Oral lesions are a cue for decreased immunity among Human Immunodeficiency Virus (HIV) positive patients. There is no cumulative data available related to the prevalence of oral soft tissue lesions...
Underestimated prevalence of HIV, hepatitis B virus (HBV), and hepatitis D virus (HDV) triple infection globally: Systematic review and meta-analysis
BACKGROUND: Hepatitis delta virus (HDV) is a satellite RNA virus that relies on hepatitis B virus (HBV) for transmission. HIV/HBV/HDV coinfection or triple infection is common and has a worse...
The current challenges affecting the quality of care of HIV/AIDS in the Middle East: Perspectives from local experts and future directions
OBJECTIVE: This report aimed to reflect the experts’ views regarding the challenges affecting the quality of care for people living with HIV in the Middle East. Besides, we integrated experts’...
Prevalence of visceral leishmaniasis among people with HIV: A systematic review and meta-analysis
Leishmaniasis is a parasitic infection expressing different clinical phenotypes. Visceral leishmaniasis (VL) is considered an opportunistic infection among people with human immunodeficiency virus (HIV). The objective of this review was...
Thirty-five years (1986–2021) of HIV/AIDS in Nigeria: bibliometric and scoping analysis
BACKGROUND: Acquired immunodeficiency syndrome (AIDS) is an acquired defect of the cellular immunity associated with the infection by the human immunodeficiency virus (HIV). The disease has reached pandemic proportion and...
Diagnostic performance of the HCV core Antigen test to identify hepatitis C in HIV-infected patients: A systematic review and meta-analysis
The standard algorithm for diagnosing hepatitis C virus (HCV) infection has two steps, an HCV antibody test for screening and a nucleic acid amplification test (NAAT) for confirmation. However, the...
Impacts of psychological wellbeing with HIV/AIDS and cancer among sexual and gender minorities: A systematic review and meta-analysis
BACKGROUND: The agony and economic strain of cancer and HIV/AIDS therapies severely impact patients’ psychological wellbeing. Meanwhile, sexual minorities experience discrimination and mental illness. LGBT individuals with cancer and HIV/AIDS...
Apolipoprotein L1 gene variants and kidney disease in patients with HIV: A systematic review and meta-analysis
Background: The risk of various types of kidney disease is significantly increased in the presence of APOL1 high-risk genotype (carriage of two risk alleles), particularly HIV-associated nephropathy (HIVAN). However, there are...
A systematic review and meta-analysis of the epidemiology of Leptospirosis in HIV uninfected and in people living with HIV from the Southern African Development Community
BACKGROUND: Leptospirosis is an occupational, neglected febrile disease of bacterial origin transmitted between humans and animals. In this manuscript we summarize available data on Leptospira infection in HIV uninfected and...
