Category Archives: Epidemiology and Determinants of Health

The prevalence and influencing factors of frailty among middle-aged and older adults with HIV/AIDS from a global perspective: A systematic review and meta-analysis

2026

Aim: Currently, frailty has become a central issue in health management among middle-aged and older people living with HIV/AIDS (PLWHA) worldwide. The objective is to develop targeted strategies to improve frailty...

Inconsistent condom use and its associated factors among female sex workers in African countries: Systematic review and meta-analysis

2026

Background Inconsistent condom use represents the most proximal behavioral risk factor for acquisition and transmission of sexually transmitted infections, including human immunodeficiency virus. However, certain situations hinder female sex workers...

Global Perspectives on Pre-Exposure Prophylaxis: A Systematic Review and Meta-Analysis of Health Care Providers’ Awareness, Willingness, and Barriers

2026

This systematic review and meta-analysis aimed to assess health care providers’ awareness, willingness, and key barriers in implementing HIV pre-exposure prophylaxis (PrEP). The review followed the Preferred Reporting Items for...

Prevalence of oral high-risk HPV and HPV16 infection among people living with HIV: A systematic review and meta-analysis

2025

Objectives: Little is known about the natural history of oral HPV in people living with HIV (PLWH). This systematic review and meta-analysis evaluated oral HPV prevalence among PLWH. Methods: Studies with ≥18-year-old...

Prevalence and associated factors of ICD/DSM-diagnosed depressive disorders among people living with HIV: A systematic review and meta-analysis

2026

Background: Depressive disorders are highly prevalent among people living with HIV (PLWH), severely impairing quality of life and antiretroviral therapy (ART) adherence. While ART advances call for reassessing depressive disorders among...

A web of risk: Multilevel factors and feedback loops (re)produce HIV ‘risk’ among gay, bisexual and other men who have sex with men—A global systematic review

2025

BACKGROUND: HIV literature shows that gay, bisexual and men who have sex with other men (GBMSM) experience inequities across social and contextual factors. Given growing inequities, this study used complex...

The burden of sarcopenia in people living with HIV: A systematic review and meta-analysis across WHO regions

2026

BACKGROUND: Sarcopenia, characterized by progressive loss of skeletal muscle mass and function, represents an underrecognized comorbidity in people living with human immunodeficiency virus, and comprehensive prevalence data across WHO regions...

Informed consent in molecular HIV epidemiology: A rapid review of the literature to identify concerns and recommendations

2026

In the United States, molecular HIV epidemiology (MHE) is a key part of the National HIV/AIDS Strategy, which incorporates the evaluation of HIV genetic sequences for cluster detection and response....

Prevalence of HIV-associated nephropathy in children: A systematic review with meta-analysis of studies published between 2004 and 2019

2026

Introduction Despite major advances in antiretroviral therapy, HIV infection remains a significant global public health challenge. HIV can directly affect the kidneys, leading to HIV-associated nephropathy in children, a condition...

HIV mortality surveillance in Nigeria, a systematic review of trends, determinants, and implications for public health policy

2026

Despite substantial progress in expanding antiretroviral therapy (ART) coverage and scaling up prevention interventions, Human Immunodeficiency Virus (HIV) related mortality remains a significant public health challenge in several high-burden settings,...

Knowledge of reproductive-age women about mother-to-child transmission of HIV and associated factors: A systematic review and meta-analysis

2026

INTRODUCTION: Despite significant efforts to manage and prevent HIV, knowledge gaps persist regarding mother-to-child transmission of HIV among women of reproductive age. Previous studies, limited in scope and producing inconsistent...

Virologic suppression among HIV-positive pregnant and lactating women receiving antiretroviral therapy in Africa: A systematic review and meta-analysis

2026

Background The elimination of mother-to-child transmission of human immunodeficiency virus (HIV) is a key global public health priority. In Africa, virologic failure among people living with HIV continues to pose a...

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