Category Archives: Neurocognitive disorders
Worldwide occurrence of HIV-associated neurocognitive disorders and its associated factors: A systematic review and meta-analysis
BACKGROUND: HIV-associated neurocognitive disorders are common in people living with HIV/AIDS and affect the adherence of patients to prescriptions, activities of daily living, and quality of life of patients. However,...
Central nervous system and neurodevelopmental outcomes of HIV + and HIV exposed children: A mini review of recent findings and lessons learned from the field
There has been an increase in research looking at neurodevelopmental/neurologic outcomes of children living with HIV (Children LWHIV) and HIV exposed but uninfected children (HEU) during an era of ART....
Impact of HIV-associated cognitive impairment on functional independence, frailty and quality of life in the modern era: A meta-analysis
HIV-associated neurocognitive disorder (HAND) is an important sequela of HIV infection. Combined antiretroviral therapy (cART) has improved the health outcomes of many people living with HIV but has given rise...
A meta-analytic review of the effect of antiretroviral therapy on neurocognitive outcomes in adults living with HIV-1 in low-and middle-income countries
HIV-associated neurocognitive impairment remains a challenge even in the era of antiretroviral therapy (ART). Over 90% of people living with HIV are in low- and middle-income countries. Hence, it is...
Meta-analysis on nicotine’s modulation of HIV-associated dementia
HIV-Associated Dementia (HAD) is a significant comorbidity that many HIV-patients face. Our study utilized QIAGEN Ingenuity Pathway Analysis (IPA) to identify and analyze molecular profiles and pathways underlying nicotine’s impact...
Sex differences in non-AIDS comorbidities among people with human immunodeficiency virus
Women are grossly underrepresented in human immunodeficiency virus (HIV) clinical and translational research. This is concerning given that people with HIV (PWH) are living longer, and thus accumulating aging-related non-AIDS...
Validity of digital assessments in screening for HIV-related cognitive impairment: A review
PURPOSE OF REVIEW: While traditional neuropsychological tests are the gold standard in screening for HIV-related cognitive impairment, computerized neuropsychological assessment devices (CNADs) offer an alternative to these time- and resource-intensive...
Immune dysregulation is associated with neurodevelopment and neurocognitive performance in HIV pediatric populations—A Scoping Review
HIV-1 is known for its complex interaction with the dysregulated immune system and is responsible for the development of neurocognitive deficits and neurodevelopmental delays in pediatric HIV populations. Considering that...
