Category Archives: Neurocognitive disorders
Human immunodeficiency virus-related peripheral neuropathy: A systematic review and meta-analysis
Background and purpose: Human immunodeficiency virus (HIV)-associated neurological syndromes occur in affected individuals as a consequence of primary HIV infection, opportunistic infections, inflammation and as an adverse effect of some...
Frequency of falls and associated risk factors in people living with HIV: a systematic review with meta-analysis and meta-regression
BACKGROUND: Falls are considered predictive marker of poorer outcomes for people living with HIV. However, the available evidences on the predictive value of falls are controversial. Our aim is to...
The prevalence of Frascati-criteria-based HIV-associated neurocognitive disorder (HAND) in HIV-Infected adults: A systematic review and meta-analysis
Background: The HIV associated mortality is decreasing in most countries due to the widespread use of antiretroviral therapy. However, HIV-associated neurocognitive disorder (HAND) remains a problematic issue that lowers the...
Proteomics and metabolomics of HIV-associated neurocognitive disorders: A systematic review
HIV-associated neurocognitive disorders (HAND) are common features of the effect of human immunodeficiency virus (HIV)-1 within the central nervous system (CNS). The underlying neuropathophysiology of HAND is incompletely known. Furthermore,...
Association between cognitive reserve and cognitive performance in people with HIV: A systematic review and meta-analysis
Cognitive reserve is a potential explanation for the disparity between brain pathology and its clinical manifestations. The main objective of this study was to estimate, based on published studies, the...
Cognitive and educational interventions for orphans and vulnerable children affected by HIV/AIDS: A meta-analysis
Orphans and vulnerable children affected by HIV/AIDS (HIV OVC) are at risk for cognitive difficulties and lack of access to education. Interventions addressing cognitive or educational outcomes for HIV OVC...
Neuropathy complication of antiretroviral therapy in HIV/AIDS patients
OBJECTIVES: Significant pain from HIV-associated sensory neuropathy (HIV-SN) affects 40% of HIV-infected individuals treated with antiretroviral therapy (ART). The most salient symptom of the neuropathy is pain, which frequently is...
Cognitive and neurologic rehabilitation strategies for central nervous system HIV infection
PURPOSE OF REVIEW: Cognitive impairment leading to disability is increasingly seen in people living with human immunodeficiency virus (PLWH). Rehabilitation can alleviate the effects of cognitive impairment upon function. The...
Interventions for Children with Neurocognitive Impairments in Resource-Limited Settings: A Systematic Review
Many children and adolescents around the world suffer from neurocognitive deficits due to chronic disorders, such as Human Immunodeficiency Virus (HIV) and malaria. Resource-limited settings exacerbate the risk of negative...
The relationship between potentially traumatic or stressful events, HIV infection and neurocognitive impairment (NCI): A systematic review of observational epidemiological studies
BACKGROUND: HIV/AIDS and potentially traumatic events (PTEs) or stressful life events (SLEs) and/or PTSD are independently associated with neurocognitive impairment (NCI). Literature suggests that HIV and PTE/SLE exposure independently and...
