Category Archives: Mental Health
Impact of HIV-associated cognitive impairment on functional independence, frailty and quality of life in the modern era: A meta-analysis
HIV-associated neurocognitive disorder (HAND) is an important sequela of HIV infection. Combined antiretroviral therapy (cART) has improved the health outcomes of many people living with HIV but has given rise...
A meta-analytic review of the effect of antiretroviral therapy on neurocognitive outcomes in adults living with HIV-1 in low-and middle-income countries
HIV-associated neurocognitive impairment remains a challenge even in the era of antiretroviral therapy (ART). Over 90% of people living with HIV are in low- and middle-income countries. Hence, it is...
A systematic review and meta-analysis on depression and associated factors among adult HIV/AIDS-positive patients attending ART clinics of Ethiopia: 2021
INTRODUCTION: Depression is the most common mental health problem in people living with the human immune virus. It ranges from 11% to 63% in low- and middle-income countries. Depression was...
Mental health and well-being of older adults living with HIV in sub-Saharan Africa: A systematic review
Objective: In this systematic review, we aimed to summarise the empirical evidence on common mental disorders (CMDs), cognitive impairment, frailty and health-related quality of life (HRQoL) among people living with HIV...
The worldwide prevalence of anxiety in acquired immune deficiency syndrome patients: A systematic review and meta-analysis
Background: Anxiety affects social, economic, and physical aspects of daily life in patients with AIDS. Therefore, it is necessary to take preventive measures and design plans to maintain their general...
Meta-analysis on nicotine’s modulation of HIV-associated dementia
HIV-Associated Dementia (HAD) is a significant comorbidity that many HIV-patients face. Our study utilized QIAGEN Ingenuity Pathway Analysis (IPA) to identify and analyze molecular profiles and pathways underlying nicotine’s impact...
A scoping review investigating relationships between depression, anxiety, and the PrEP care continuum in the United States
Men who have sex with men and transgender women in the United States are at increased risk for HIV and may benefit from pre-exposure prophylaxis (PrEP), a once-a-day pill to...
Psychotherapy for comorbid depression and somatic disorders: A systematic review and meta-analysis
BACKGROUND: The treatment of depression in patients with somatic disorders is crucial, given its negative impact on quality of life (QoL), functioning, and even on the somatic disease prognosis. We...
Immune dysregulation is associated with neurodevelopment and neurocognitive performance in HIV pediatric populations—A Scoping Review
HIV-1 is known for its complex interaction with the dysregulated immune system and is responsible for the development of neurocognitive deficits and neurodevelopmental delays in pediatric HIV populations. Considering that...
Sex differences in non-AIDS comorbidities among people with human immunodeficiency virus
Women are grossly underrepresented in human immunodeficiency virus (HIV) clinical and translational research. This is concerning given that people with HIV (PWH) are living longer, and thus accumulating aging-related non-AIDS...
Validity of digital assessments in screening for HIV-related cognitive impairment: A review
PURPOSE OF REVIEW: While traditional neuropsychological tests are the gold standard in screening for HIV-related cognitive impairment, computerized neuropsychological assessment devices (CNADs) offer an alternative to these time- and resource-intensive...