Category Archives: Mental Health

Health-related quality of life in patients with different diseases measured with the EQ-5D-5L: A systematic review

2021

Background: The EQ-5D-5L is a generic preference-based questionnaire developed by the EuroQol Group to measure health-related quality of life (HRQoL) in 2005. Since its development, it has been increasingly applied...

Executive function in HIV-affected children and adolescents: A systematic review and meta-analyses

2021

This review aimed to determine: whether EF is affected in children and adolescents (2–24-years-old) with perinatal HIV infection, perinatal HIV exposure without infection, and behaviourally acquired HIV. A systematic review...

Interventions addressing depression and HIV-related outcomes in people with HIV

2021

PURPOSE OF REVIEW: People with HIV (PWH) are more likely to experience depression than those without HIV. Depression is not only distressing and interfering in and of itself, but it...

Neurological development of children who are HIV-exposed and uninfected

2021

Widespread use of antiretroviral drugs for pregnant/breastfeeding females with human immunodeficiency virus (HIV) has led to declining vertical transmission. Despite being HIV-uninfected, the increasing number of children who are HIV-exposed...

Prevalence of suicidal ideation, suicide attempt, and suicide plan among HIV/AIDS: A systematic review and meta-analysis

2021

BACKGROUND: Suicidality is common in people living with HIV/AIDS. However, the prevalence estimates of the suicidality vary between studies. Here, we performed a systematic review and estimated the prevalence of...

A review of interventions to enhance HIV medication adherence

2021

PURPOSE OF REVIEW: Adherence to antiretroviral treatment (ART) is crucial for a successful HIV treatment. Unfortunately, it is estimated that 45% of persons living with HIV (PLWH) have poor adherence...

Interventions to address the mental health of adolescents and young adults living with or affected by HIV: State of the evidence

2021

INTRODUCTION: Adolescents and young adults (AYA) remain vulnerable to HIV-infection and significant co-morbid mental health challenges that are barriers to treatment and prevention efforts. Globally millions of AYA are living...

Intervening for HIV prevention and mental health: A review of global literature

2021

INTRODUCTION: Numerous effective HIV prevention options exist, including behaviour change interventions, condom promotion and biomedical interventions, like voluntary medical male circumcision and pre-exposure prophylaxis. However, populations at risk of HIV...

Prevalence and factors associated with common mental disorders in young people living with HIV in sub-Saharan Africa: A systematic review

2021

INTRODUCTION: Common mental disorders (CMDs) particularly depression and anxiety, are highly comorbid with HIV also in young people living with HIV (YLWH). In sub-Saharan Africa (SSA) where most YLWH reside,...

Mental health interventions for persons living with HIV in low- and middle-income countries: A systematic review

2021

INTRODUCTION: Addressing the intersection between mental health and HIV is critical for the wellbeing of persons living with HIV (PLWH). This systematic review synthesized the literature on mental health interventions...

International HIV dementia scale for HIV-associated neurocognitive disorders: A systematic review and meta-analysis

2021

The present study aims to systematically review the evidence on the accuracy of the International HIV Dementia Scale (IHDS) test for diagnosing human immunodeficiency virus (HIV)-associated neurocognitive disorders (HAND) and...

Cerebrospinal fluid immune markers and HIV-associated neurocognitive impairments: A systematic review

2021

HIV-1 is responsible for the development of a spectrum of cognitive impairments known as HIV-associated neurocognitive disorder (HAND). In the era of antiretroviral therapy (ART), HAND remains prevalent in people...

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