Category Archives: Mental Health

Efavirenz-based regimens in antiretroviral-naive HIV-infected patients: A systematic review and meta-analysis of randomized controlled trials

2015

Efavirenz, a non-nucleoside reverse-transcriptase inhibitor (NNRTI) is one of the most commonly prescribed antiretroviral drugs. The present article provides a systematic overview and meta-analysis of clinical trials comparing efavirenz and...

Which psychological factors are related to HIV testing? A quantitative systematic review of global studies

2016

Deciding to test for HIV is necessary for receiving HIV treatment and care among those who are HIV-positive. This article presents a systematic review of quantitative studies on relationships between...

Improving mental health among people living with HIV: A review of intervention trials in low- and middle-income countries

2015

People living with HIV (PLWH) experience greater psychological distress than the general population. Evidence from high-incomes countries suggests that psychological interventions for PLWH can improve mental health symptoms, quality of...

Comparative safety and neuropsychiatric adverse events associated with efavirenz use in first-line antiretroviral therapy: A systematic review and meta-analysis of randomized trials

2015

INTRODUCTION: Efavirenz (EFV) is widely used for the treatment of antiretroviral-naive HIV-positive individuals, but there are concerns about the risk of adverse neuropsychiatric events. We systematically reviewed the safety of...

Depression and adherence to antiretroviral therapy in low-, middle- and high-income countries: A systematic review and meta-analysis

2014

We investigated the associations between depressive symptoms and adherence to antiretroviral therapy (ART) among people living with HIV (PLHIV). We searched the PubMed, EMBASE and Cochrane CENTRAL databases for studies...

Validity of cognitive screens for HIV-associated neurocognitive disorder: A systematic review and an informed screen selection guide.

2013

Various screening tools have been proposed to identify HIV-Associated Neurocognitive Disorder (HAND). However, there has been no systematic review of their strengths and weaknesses in detecting HAND when compared to...

Evidence informing the intersection of HIV, aging and health: A scoping review

2014

The growing number of people over age 50 with HIV requires research, policy, and practice to develop a more comprehensive understanding of the health consequences of HIV in older individuals....

Differential genotypic evolution of HIV-1 quasispecies in cerebrospinal fluid and plasma: A systematic review

2013

HIV-1 enters the central nervous system by passing the blood-brain barrier during primary infection. Despite the introduction of combination antiretroviral therapy, the prevalence of HIV-associated neurocognitive disorders remains high and...

Pharmacologic management of human immunodeficiency virus wasting syndrome

2014

Pharmacologic interventions for human immunodeficiency virus (HIV) wasting have been studied since the 1990s, but the results of these interventions have been difficult to compare because the studies used different...

The relationship between HIV and prevalence of disabilities in sub-Saharan Africa: Systematic review

2015

OBJECTIVE: To systematically review evidence on the prevalence and risk of disabilities among children and adults living with HIV in sub-Saharan Africa. METHODS: Articles were identified from 1980 to June...

Psychosocial, mental health, and behavioral issues of aging with HIV

2014

PURPOSE OF REVIEW: People with HIV continue to live with the health consequences of an episodic illness that limits their ability to fully participate in society, particularly for the growing...

Systematic review of neuroimaging studies in vertically transmitted HIV positive children and adolescents

2014

One of the most serious consequences of vertical HIV-infection is its impact on the central nervous system (CNS). Although much work has been done to elucidate the complex mechanism of...

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