Category Archives: Population(s)
Safety and efficacy of abacavir for treating infants, children, and adolescents living with HIV: A systematic review and meta-analysis
Background: Abacavir is a nucleoside reverse transcriptase inhibitor recommended in paediatric HIV care. We assessed the safety and efficacy profile of abacavir used in first, second, or subsequent lines of treatment...
Adherence to option B+ and its association with disclosure status and counseling among HIV-positive pregnant and lactating women in Ethiopia: Systematic review and meta-analysis
Objectives: This systematic review and meta-analysis aimed to assess the pooled estimate of option B+ level of adherence and its association with disclosure status and counseling among pregnant and lactation women...
Increased risk of sexually transmitted infections in men who have sex with men taking preexposure prophylaxis: A meta-analysis
BACKGROUND: Men who have sex with men (MSM) are a priority population for preexposure prophylaxis (PrEP) for HIV prevention. We summarized the surveillance data from the studies of MSM taking...
Prevalence and global trends of polypharmacy among people living with HIV: A systematic review and meta-analysis
Background: There has been a rising prevalence of polypharmacy among people living with HIV (PLWH). Uncertainty however remains regarding the exact estimates of polypharmacy among these cohorts of patients. Methods: We conducted...
Measuring and addressing stigma within HIV interventions for people who use drugs: A scoping review of recent research
PURPOSE OF REVIEW: Persistent stigma remains a crucial barrier to HIV prevention and treatment services among people who use drugs (PWUD), particularly for those living with or at-risk for HIV....
Ingestible electronic sensors for monitoring real-time adherence to HIV pre-exposure prophylaxis and antiretroviral therapy
PURPOSE OF REVIEW: This review summarizes the recent advancements and future directions of digital pill systems (DPS) – which utilize ingestible sensors to directly measure medication ingestion events in real-time...
HIV voluntary counseling and testing (VCT-HIV) effectiveness for sexual risk-reduction among key populations: A systematic review and meta-analysis
Background: HIV disproportionately affects people who inject drugs, transgender people, sex workers, men who have sex with men, and incarcerated people. Recognized as key populations (KP), these groups face increased impact...
Pediatrics HIV-positive status disclosure and its predictors in Ethiopia: A systematic review and meta-analysis
INTRODUCTION: HIV-positive status disclosure for children is challenging for family members, guardians, and healthcare professionals. Disclosure is very challenging, particularly for children, yet no systematic synthesis of evidence accurately measures...
Condom use and risk factors of inconsistent or low use of the condoms during heterosexual anal intercourse in sub-Saharan Africa: A scoping review
BACKGROUND: Anal intercourse (AI) has been reported to be the riskiest among other sexual intercourses in spreading human immunodeficiency virus (HIV) and the risk could be minimized by the use...
Screening performance of C-reactive protein for active pulmonary tuberculosis in HIV-positive patients: A systematic review with a meta-analysis
BACKGROUND: Tuberculosis (TB) is the leading infectious cause of mortality worldwide. In the last years, resistant strains of the etiological agent, Mycobacterium tuberculosis, have emerged, thus demanding more triage tests...
The performance of using dried blood spot specimens for HIV-1 viral load testing: A systematic review and meta-analysis
BACKGROUND: Accurate routine HIV viral load testing is essential for assessing the efficacy of antiretroviral treatment (ART) regimens and the emergence of drug resistance. While the use of plasma specimens...
The HIV pre-exposure prophylaxis continuum of care among women who inject drugs: A systematic review
INTRODUCTION: People who inject drugs have a substantial risk for HIV infection, especially women who inject drugs (WWID). HIV pre-exposure prophylaxis (PrEP), a highly-effective HIV prevention drug, is uncommonly studied...
