Category Archives: Population(s)

HIV seroprevalence in five key populations in Europe: A systematic literature review, 2009 to 2019

2021

Background: In Europe, HIV disproportionately affects men who have sex with men (MSM), people who inject drugs (PWID), prisoners, sex workers, and transgender people. Epidemiological data are primarily available from...

Current approaches to HIV vaccine development: A narrative review

2021

INTRODUCTION: The development of an effective vaccine to protect against HIV is a longstanding global health need complicated by challenges inherent to HIV biology and to the execution of vaccine...

The likelihood of severe COVID-19 outcomes among PLHIV with various comorbidities: A comparative frequentist and Bayesian meta-analysis approach

2021

INTRODUCTION: The SARS-CoV-2 virus can currently pose a serious health threat and can lead to severe COVID-19 outcomes, especially for populations suffering from comorbidities. Currently, the data available on the...

HIV protease inhibitors and insulin sensitivity: A systematic review and meta-analysis of randomized controlled trials

2021

Background: Protease inhibitors (PIs) are believed to affect insulin sensitivity. We aimed to analyze the effect of PIs on insulin sensitivity and the onset of diabetes mellitus (DM) in patients with...

HIV prevalence among non-injecting people who use drugs and related factors in Iran: A systematic review and meta-analysis

2021

Issues: This systematic review aimed to provide an updated estimate on the prevalence of human immunodeficiency virus (HIV) infection among non-injecting people who use drugs (PWUD) and the various subgroups and...

Assessing inclusion of trans people in HIV national strategic plans: A review of 60 high HIV prevalence countries

2021

INTRODUCTION: Trans people are disproportionately impacted by HIV yet have not been adequately prioritized in national HIV responses or policy documents. This review aims to understand the extent of meaningful...

HIV response interventions that integrate HIV molecular cluster and social network analysis: A systematic review

2021

Due to improved efficiency and reduced cost of viral sequencing, molecular cluster analysis can be feasibly utilized alongside existing human immunodeficiency virus (HIV) prevention strategies. The goal of this paper...

Pre-exposure prophylaxis uptake, adherence, and persistence: A narrative review of interventions in the U.S

2021

Since 2012, HIV pre-exposure prophylaxis (PrEP) has been available to prevent HIV transmission; yet, uptake, adherence, and persistence to PrEP have been suboptimal. This narrative review examines the latest interventions...

Meta-analysis on nicotine’s modulation of HIV-associated dementia

2021

HIV-Associated Dementia (HAD) is a significant comorbidity that many HIV-patients face. Our study utilized QIAGEN Ingenuity Pathway Analysis (IPA) to identify and analyze molecular profiles and pathways underlying nicotine’s impact...

A scoping review investigating relationships between depression, anxiety, and the PrEP care continuum in the United States

2021

Men who have sex with men and transgender women in the United States are at increased risk for HIV and may benefit from pre-exposure prophylaxis (PrEP), a once-a-day pill to...

Cognitive intra-individual variability in HIV: An integrative review

2021

Nearly 30–50% of people living with HIV experience HIV-Associated Neurocognitive Disorder (HAND). HAND indicates performance at least one standard deviation below the normative mean on any two cognitive domains. This...

HIV/AIDS stigma and psychological well-being after 40 years of HIV/AIDS: A systematic review and meta-analysis

2021

Background In June 2021, 40 years have passed since the first cases of HIV infection were detected. Nonetheless, people living with HIV (PLWH) still suffer from intense HIV-related distress and...

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