Category Archives: Population(s)
Uptake of couples HIV testing and counselling among heterosexual couples in Sub-Saharan Africa: A systematic review and meta-analysis
There is a need for further research to inform policy and practice on Couples HIV Testing and Counselling (CHTC) in Sub-Saharan Africa (SSA). The aim of this systematic review and...
How effective are approaches to migrant screening for infectious diseases in Europe? A systematic review
Rates of migration to Europe, and within Europe, have increased in recent years, with considerable implications for health systems. Migrants in Europe face a disproportionate burden of tuberculosis, HIV, and...
Systematic review of the performance and clinical utility of point of care HIV-1 RNA testing for diagnosis and care
BACKGROUND: Point of-care (POC) HIV-1 RNA tests which are accurate and easy to use with limited infrastructure are needed in resource-limited settings (RLS). We systematically reviewed evidence of POC test...
Tenofovir-associated kidney disease in Africans: A systematic review
BACKGROUND: Data on chronic kidney disease development in HIV infection is important towards building a comprehensive knowledge of HIV, ageing and polypharmacy in Africa. Several previous studies on tenofovir-associated kidney...
Systematic review and meta-analysis of treatment interruptions in HIV-1 infected patients receiving antiretroviral therapy: Implications for future HIV cure trials
BACKGROUND: Safety and tolerability of analytical treatment interruptions (ATIs) as a vital part of HIV-1 cure studies are discussed. We analyzed current evidence for occurrence of adverse events (AEs) during...
Meta-analyses of HIV prevention interventions targeting improved partner communication: Effects on partner communication and condom use frequency outcomes
Behavioral HIV prevention interventions designed to improve safer-sex communication skills with sexual partners may enhance engagement in protective behaviors and reduce HIV/STI risk. The current meta-analyses examined the efficacy of...
Second-line HIV treatment failure in sub-Saharan Africa: A systematic review and meta-analysis
BACKGROUND: Increased second-line antiretroviral therapy (ART) failure rate narrows future options for HIV/AIDS treatment. It has critical implications in resource-limited settings; including sub-Saharan Africa (SSA) where the burden of HIV-infection...
Causal effects of education on sexual and reproductive health in low and middle-income countries: A systematic review and meta-analysis
Background: Despite strong theoretical grounding, important gaps in knowledge remain regarding the degree to which there is a causal relationship between education and sexual and reproductive health, as many claims have...
Are policy initiatives aligned to meet UNAIDS 90-90-90 targets impacting HIV testing and linkages to care? Evidence from a systematic review
Background: The Joint United Nations Programme on HIV/AIDS (UNAIDS) Fast-Track initiative seeks to eliminate AIDS as a health threat by 2030, with its focus on UNAIDS 90-90-90 targets. Effective policies and...
Prevalence and factors associated with fertility desires/intentions among individuals in HIV-serodiscordant relationships: A systematic review of empirical studies
INTRODUCTION: Better knowledge about fertility desires/intentions among HIV-serodiscordant partners who face unique challenges when considering childbearing may be helpful in the development of targeted reproductive interventions. The aim of this...
Scaling up HIV self-testing in sub-Saharan Africa: A review of technology, policy and evidence
PURPOSE OF REVIEW: HIV self-testing (HIVST) can provide complementary coverage to existing HIV testing services and improve knowledge of status among HIV-infected individuals. This review summarizes the current technology, policy...
