Category Archives: Population(s)

Prevalence and incidence of new-onset seizures and epilepsy in patients with human immunodeficiency virus (HIV): Systematic review and meta-analysis

2019

BACKGROUND: The prevalence and incidence of seizures are substantially higher in patients with human immunodeficiency virus (HIV) compared with the general population and is associated with higher mortality rates. Despite...

Implementation science and stigma reduction interventions in low- and middle-income countries: A systematic review

2019

BACKGROUND: Interventions to alleviate stigma are demonstrating effectiveness across a range of conditions, though few move beyond the pilot phase, especially in low- and middle-income countries (LMICs). Implementation science offers...

The efficacy of post-exposure prophylaxis (PEP) for HIV

2019

Key take-home messages PEP initiated soon after exposure can reduce the risk of HIV seroconversion after occupational and non-occupational exposures, provided adherence to medications is sufficient. Evidence suggests that individuals...

Optimizing pediatric dosing recommendations and treatment management of antiretroviral drugs utilizing therapeutic drug monitoring data in children living with HIV

2019

INTRODUCTION: This review summarises the current dosing recommendations for antiretroviral drugs (ARVs) in the international pediatric guidelines of the World Health Organisation (WHO), US Department of Health and Human Services...

The burden of vaccine-preventable diseases among HIV-infected and HIV-exposed children in sub-Saharan Africa: a systematic review and meta-analysis

2019

There are knowledge gaps regarding evidence-based research on the burden of vaccine-preventable diseases among human immunodeficiency virus (HIV)-infected and HIV-exposed children aged

Effects of aerobic and resistance exercise on cardiovascular parameters for people living with HIV: A meta-analysis

2019

People living with HIV (PLWH) have limited exercise capacity because of anemia, neuromuscular disorders, and pulmonary limitations. We used a meta-analysis to examine the effect of aerobic and resistance exercise...

Can mental health treatments help prevent or reduce intimate partner violence in low- and middle-income countries? A systematic review

2019

BACKGROUND: Epidemiological research suggests an interrelationship between mental health problems and the (re)occurrence of intimate partner violence (IPV). However, little is known about the impact of mental health treatments on...

The impact of location on implementation of HIV/STI prevention interventions among LGBTQ communities

2019

Key take-home messages The characteristics of a location, including segregation, community-level stigma, and infrastructural resources, may influence HIV service utilization and the HIV continuum of care among men who have...

Adverse effects of chronic treatment with the main subclasses of highly active antiretroviral therapy: A systematic review

2019

OBJECTIVES: The aim of the review was to elucidate the adverse effects of chronic treatment with the main subclasses of highly active antiretroviral therapy (HAART). METHODS: A systematic review was...

Alcohol misuse and illicit drug use among occupational groups at high risk of HIV in sub-Saharan Africa: A systematic review

2019

Key occupational groups in sub-Saharan Africa (SSA) are at increased risk of HIV, and may be at increased risk of substance use. In January 2018, we systematically searched for studies...

Behavioral interventions to enhance PrEP uptake among black men who have sex with men: A review

2019

In the United States, nearly 500,000 men who have sex with men (MSM) are at risk of contracting HIV. Men who have sex with men constitute 70% of all new...

Dolutegravir-rilpivirine, dual antiretroviral therapy for the treatment of HIV-1 infection

2019

OBJECTIVE: To review the efficacy and safety of dolutegravir (DTG) with rilpivirine (RPV) as a dual therapy regimen in the treatment of HIV-1 infection. DATA SOURCES: A literature search was...

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