Category Archives: Population(s)

Primary prophylaxis for cryptococcal meningitis and impact on mortality in HIV: A systematic review and meta-analysis

2013

Aim: To determine the role of primary antifungal prophylaxis in the prevention of cryptococcal meningitis and all-cause mortality in advanced HIV infection. Materials & methods: This was a systematic review...

Equity in utilization of antiretroviral therapy for HIV-infected people in South Africa: A systematic review

2014

INTRODUCTION: About half a million people in South Africa are deprived of antiretroviral therapy (ART), and there is little systematic knowledge on who they are – e.g. by severity of...

Beyond the bisexual bridge: Sexual health among U.S. men who have sex with men and women

2014

CONTEXT: Men who have sex with both men and women (MSMW) experience health problems in ways that distinguish them from men who only have sex with men (MSM) and men...

Adherence to antiretroviral therapy in adolescents living with HIV: Systematic review and meta-analysis

2014

OBJECTIVE: Adolescent and young adult (AYA) populations (12-24 years) represent over 40% of new HIV infections globally. Adolescence is sometimes characterized by high-risk sexual behaviour and a lack of engagement...

A systematic review of a single-class maintenance strategy with nucleoside reverse transcriptase inhibitors in HIV/AIDS

2014

BACKGROUND: Single drug class regimens with nucleotide reverse transcriptase inhibitors (NRTIs) are generally not recommended as initial therapy, because they were inferior compared to therapy with 2 NRTIs plus efavirenz....

Effectiveness of ART and condom use for prevention of sexual HIV transmission in serodiscordant couples: A systematic review and meta-analysis

2014

BACKGROUND: Consistent and correct condom use and suppressive antiretroviral therapy for the infected partner are two of the primary strategies recommended for prevention of heterosexual HIV transmission in serodiscordant couples...

Mobile phone text messaging interventions for HIV and other chronic diseases: An overview of systematic reviews and framework for evidence transfer

2015

Background Strong international commitment and the widespread use of antiretroviral therapy have led to higher longevity for people living with human immune deficiency virus (HIV). Text messaging interventions have been...

Factors impacting HIV testing: A review – perspectives from Australia, Canada, and the UK

2015

With the current global focus on strengthening HIV prevention through greater testing and treatment uptake, it is increasingly salient to identify and address barriers to testing. A review of the...

Substance abuse treatment in persons with HIV/AIDS: Challenges in managing triple diagnosis

2014

Clinical management of HIV must account for the “triple diagnosis” of HIV, psychiatric diagnosis, and substance use disorders and requires integrated treatment services that focus beyond just mitigation of substance...

Choice of antiretroviral drugs for postexposure prophylaxis for adults and adolescents: A systematic review

2015

BACKGROUND: The choice of preferred regimens for human immunodeficiency virus postexposure prophylaxis (PEP) has evolved over the last 2 decades as more data have become available regarding the safety and...

Systematic review of stigma reducing interventions for African/Black diasporic women

2015

INTRODUCTION: Literature indicates that racism, sexism, homophobia and HIV-related stigma have adverse impacts on health, well-being, and quality of life among HIV-positive women of African descent (African/Black diaspora). However, limited...

A systematic review of the effects of visual inspection with acetic acid, cryotherapy, and loop electrosurgical excision procedures for cervical dysplasia in HIV-infected women in low- and middle-income countries

2015

BACKGROUND: Cervical cancer, almost all of which is caused by human papillomavirus, accounts for 12% of female cancers worldwide and is more common among HIV-infected women. Nine of 10 deaths...

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