Category Archives: Population(s)
Review of human immunodeficiency virus type 1-related opportunistic infections in sub-Saharan Africa
Understanding the natural history of human immunodeficiency virus type 1 (HIV-1) and opportunistic infections in sub-Saharan Africa is necessary to optimize strategies for the prophylaxis and treatment of opportunistic infections...
Invasive non-typhoidal salmonella disease: An emerging and neglected tropical disease in Africa
Invasive strains of non-typhoidal salmonellae have emerged as a prominent cause of bloodstream infection in African adults and children, with an associated case fatality of 20-25%. The clinical presentation of...
The impact of community mobilisation on HIV prevention in middle and low income countries: A systematic review and critique.
While community mobilisation (CM) is increasingly advocated for HIV prevention, its impact on measurable outcomes has not been established. We performed a systematic review of the impact of CM within...
Interventions to prevent HIV/AIDS among adolescents in less developed countries: Are they effective?
The objective of this study was to summarize and critically assess the effects of interventions to prevent HIV/AIDS among adolescents in less developed countries. Reports of studies that evaluated interventions...
Changes in hematologic parameters and efficacy of thymidine analogue-based, highly active antiretroviral therapy: A meta-analysis of six prospective, randomized, comparative studies
Background: Hematologic changes that occur with HIV infection and antiretroviral therapy may impact the quality of life of patients and have been associated with morbidity and mortality. The management of...
Behavioral interventions to reduce incidence of HIV, STD, and pregnancy among adolescents: A decade in review
PURPOSE: To review adolescent sexual risk-reduction programs that were evaluated using quasi-experimental or experimental methods and published in the 1990s. We describe evaluated programs and identify program and evaluation issues...
Prevalence of sexually transmitted co-infections in people living with HIV/AIDS: Systematic review with implications for using HIV treatments for prevention.
Sexually transmitted co-infections increase HIV infectiousness through local inflammatory processes. The prevalence of STI among people living with HIV/AIDS has implications for containing the spread of HIV in general and...
CCL3L1 copy number variation and susceptibility to HIV-1 infection: A meta-analysis
Although several studies have investigated whether CCL3L1 copy number variation (CNV) influences the risk of HIV-1 infection, there are still no clear conclusions. Therefore, we performed a meta-analysis using two...
A systematic review of published evidence on intervention impact on condom use in sub-Saharan Africa and Asia
OBJECTIVE: There has been much debate about the value of condoms in HIV/STI programming. This should be informed by evidence about intervention impact on condom use, but there is limited...
