Category Archives: Population(s)
Morbidity and mortality in tuberculosis associated immune reconstitution inflammatory syndrome in children living with HIV: A narrative review
Tuberculosis-associated immune reconstitution syndrome (TB-IRIS) is an increasingly recognized complication of children living with HIV who are receiving treatment for active tuberculosis (TB). The purpose of the study was to...
Attrition one year after starting antiretroviral therapy before and after the programmatic implementation of HIV “Treat All” in Sub-Saharan Africa: A systematic review and meta-analysis
Introduction Evidence on the real-world effects of “Treat All” on attrition has not been systematically reviewed. We aimed to review existing literature to compare attrition 12 months after antiretroviral therapy (ART)...
Systematic review of prevalence and risk factors of transfusion transmissible infections among blood donors, and blood safety improvements in Southern Africa
Blood and blood products are listed as one of the essential medicines by the World Health Organization (WHO). In addition to inadequate supply, most sub-Saharan Africa (SSA) nations fail to...
The association between HIV infection and precancerous cervical lesion. A systematic review and meta-analysis of case-control studies
BACKGROUND: The effect of human immunodeficiency virus (HIV) on precancerous cervical lesion is not consistent across studies. Besides to the variability in the presence of a significant association between HIV...
Global prevalence of chronic pain in women with HIV: A systematic review and meta-analysis
Chronic pain is common among people with human immunodeficiency virus (HIV) and detrimental to quality of life and overall health. It is often underdiagnosed, undertreated, and frankly dismissed in women...
HIV testing disruptions and service adaptations during the COVID-19 pandemic: A systematic literature review
Access to treatment and care in safe clinical settings improves people’s lives with HIV. The COVID-19 pandemic disrupted vital HIV programs and services, increasing the risk of adverse health outcomes...
Pharmacokinetics of antiretroviral drugs in older people living with HIV: A systematic review
Background and objective: The life expectancy of people living with HIV (PLWHIV) has significantly improved in recent decades, mostly due to antiretroviral (ARV) therapy. Aging can affect the pharmacokinetics of drugs...
Global associations of key populations with HIV-1 recombinants: A systematic review, global survey, and individual participant data meta-analysis
INTRODUCTION: Global HIV infections due to HIV-1 recombinants are increasing and impede prevention and treatment efforts. Key populations suffer most new HIV infections, but their role in the spread of...
Geographic and population distributions of HIV-1 and HIV-2 circulating subtypes: A systematic literature review and meta-analysis (2010–2021)
BACKGROUND: HIV continues to be a major source of morbidity and mortality. Among the main challenges faced by prophylactic HIV vaccine development are the high rates of genetic mutation and...
MiRNA expression profiling in HIV pathogenesis, disease progression and response to treatment: A systematic review
Aim: A systematic review was conducted to identify the association of miRNA expression with HIV pathogenesis, progression and treatment. Methods: A search of articles was conducted in MEDLINE®, Cochrane Central Register of Controlled...
Incidence and prevalence of hepatitis C virus among HIV-negative gay and bisexual men using HIV pre-exposure prophylaxis (PrEP): A systematic review and meta-analysis
BACKGROUND: Gay and bisexual men using HIV pre-exposure prophylaxis (PrEP) are at increased risk for sexually transmissible infections. Hepatitis C virus (HCV) risk among PrEP users is less clear. We...
HIV stigma reduction interventions among health care providers and students in different countries: A systematic review
BACKGROUND: Health care providers’ stigmatizing attitudes are obstacles to patients’ well-being and quality of life. Dealing with HIV-related stigma and understanding the impact of feasible interventions on reducing stigmatizing attitudes...
