Category Archives: People who use drugs

Experiences of the HIV cascade of care among indigenous peoples: A systematic review

2019

Indigenous leaders remain concerned that systemic oppression and culturally unsafe care impede Indigenous peoples living with HIV from accessing health services that make up the HIV cascade of care. We...

Elimination of HIV transmission through novel and established prevention strategies among people who inject drugs

2018

Despite the effectiveness of existing HIV prevention strategies for people who inject drugs (PWID), uncontrolled outbreaks of HIV among this group are common and occur around the world. In this...

Trends and emerging directions in HIV risk and prevention research in the Philippines: A systematic review of the literature

2018

BACKGROUND: The Philippines is experiencing one of the fastest growing epidemics globally. Evidence-based public health policies are needed. To describe the public health literature on HIV risk groups and prevention...

A meta-analysis of the association between needle exchange programs and HIV seroconversion among injection drug users

2018

We assessed the association between different levels of needle exchange program (NEP) use and human immunodeficiency virus (HIV) seroconversion in the injecting drug user (IDU) population using meta-analysis to aggregate...

A systematic review of adherence to oral pre-exposure prophylaxis for HIV — How can we improve uptake and adherence?

2018

INTRODUCTION: Oral pre-exposure prophylaxis (PrEP) is an effective strategy to reduce the risk of HIV transmission in high risk individuals. However, the effectiveness of oral pre-exposure prophylaxis is highly dependent...

Cost-effectiveness of HIV screening in high-income countries: A systematic review

2018

INTRODUCTION: Over 2 million people in high-income countries live with HIV. Early diagnosis and treatment present benefits for infected subjects and reduce secondary transmissions. Cost-effectiveness analyses are important to effectively...

Evolving models and ongoing challenges for HIV preexposure prophylaxis implementation in the United States

2018

BACKGROUND: The use of preexposure prophylaxis (PrEP) for HIV prevention was approved by the Food and Drug Administration in 2012, but delivery to at-risk persons has lagged. This critical review...

HCV reinfection rates among people who use drugs

2014

Key take-home messages HCV affects people differently. Some are able to spontaneously clear the virus on their own; others develop chronic HCV infection that affects their health and requires treatment....

HIV and STI testing among Indigenous women and women who inject drugs

2016

Key take-home messages Rates of HIV and other sexually transmitted and bloodborne infections are high among Indigenous women and women who inject drugs. For women who use drugs, centres that...

Hepatitis C reinfection after successful treatment

2016

Key take-home messages HCV reinfection rates vary widely. Reinfection depends on the extent to which an individual engages in high risk activities after having achieved sustained virologic response through treatment....

Chest compressions and rescue breathing when administering naloxone in opioid overdose

2016

Key take-home messages Opioid overdoses cause respiratory failure (a reduction or stop in breathing), which can lead to cardiac arrest. In the event of a suspected opioid overdose, bystanders should...

Engaging law enforcement in harm reduction programs for people who inject drugs

2016

Key take-home messages Injection drug use is a major contributor to the spread of HIV and Hepatitis C in Canada. Laws and policing practices that govern injection drug use influence...

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