Category Archives: General HIV- population

Reviews on HIV- people that explore topics including risk, screening, and prevention

The willingness to participate in biomedical research involving human beings in low- and middle-income countries: A systematic review

2019

OBJECTIVES: To systematically review reasons for the willingness to participate in biomedical human subjects research in low- and middle-income countries (LMICs). METHODS: Five databases were systematically searched for articles published...

Economic evaluations of pre- and post-exposure prophylaxis for HIV

2019

Key take-home messages Economic evaluations of health care interventions can inform resource allocation and policy development. However, interpreting and generalizing results can be challenging. PrEP can be cost-effective or cost-saving...

Transmission of drug-resistant tuberculosis in HIV-endemic settings

2018

The emergence and expansion of the multidrug-resistant tuberculosis epidemic is a threat to the global control of tuberculosis. Multidrug-resistant tuberculosis is the result of the selection of resistance-conferring mutations during...

Advances in the understanding of mycobacterium tuberculosis transmission in HIV-endemic settings

2018

Tuberculosis claims more human lives than any other infectious disease. This alarming epidemic has fuelled the development of novel antimicrobials and diagnostics. However, public health interventions that interrupt transmission have...

Effects of migration on risky sexual behavior and HIV acquisition in South Africa: A systematic review and meta-analysis, 2000-2017

2018

While human mobility has been implicated in fueling the HIV epidemic in South Africa, the link between migration and HIV has not been systematically reviewed and quantified. We conducted a...

STI health disparities: A systematic review and meta-analysis of the effectiveness of preventive interventions in educational settings

2018

The purpose of this systematic review and meta-analysis was to address disparities related to sexual health among students by examining the effectiveness of sexually transmitted infection (STI) preventive interventions in...

Effect of Xpert MTB/RIF on clinical outcomes in routine care settings: Individual patient data meta-analysis

2019

BACKGROUND: Xpert MTB/RIF, the most widely used automated nucleic acid amplification test for tuberculosis, is available in more than 130 countries. Although diagnostic accuracy is well documented, anticipated improvements in...

Cost effectiveness of HIV and sexual reproductive health interventions targeting sex workers: A systematic review

2018

Background: Sex workers have high incidences of HIV and other sexually transmitted diseases. Although, interventions targeting sex workers have shown to be effective, evidence on which strategies are most cost-effective...

Effectiveness of HIV testing interventions for high-risk populations

2013

Key take-home messages People infected with HIV who are unaware of their HIV status may be driving the epidemic in high-risk populations. Interventions that promote the uptake of HIV testing...

The effect of alcohol consumption on ART adherence and sexual risk behaviours among men who have sex with men

2016

Key take-home messages Among people living with HIV, alcohol consumption can have an impact on viral load and CD4 counts and affect adherence to antiretroviral regimens. Many studies have found...

The use of geosocial networking smartphone applications and the risk of sexually transmitted infections among men who have sex with men: A systematic review and meta-analysis

2018

BACKGROUND: Geosocial networking smartphone applications (apps) are popular tools for seeking sexual partners among men who have sex with men (MSM). We evaluated app use and risk of sexually transmitted...

Gay men’s attitudes to and perceptions of pre-exposure prophylaxis (PrEP) and post-exposure prophylaxis (PEP)

2013

Key take-home messages There were fewer studies published on the potential use of non-occupational PEP (nPEP) among men who have sex with men than those on PrEP. Although 47% to...

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