Category Archives: General HIV- population
Reviews on HIV- people that explore topics including risk, screening, and prevention
Chemsex behaviours among men who have sex with men: A systematic review of the literature
BACKGROUND: ‘Chemsex’ is the use of drugs before or during planned sexual events to facilitate, enhance, prolong and sustain the experience. Drugs associated with chemsex are methamphetamine, GHB/GBL, mephedrone, cocaine...
Anthroponotic transmission of cryptosporidium parvum predominates in countries with poorer sanitation: A systematic review and meta-analysis
BACKGROUND: Globally cryptosporidiosis is one of the commonest causes of mortality in children under 24 months old and may be associated with important longterm health effects. Whilst most strains of...
Risk of sexual transmission of human immunodeficiency virus with antiretroviral therapy, suppressed viral load and condom use: A systematic review
BACKGROUND: The Public Health Agency of Canada reviewed sexual transmission of HIV between serodiscordant partners to support examination of the criminal justice system response to HIV nondisclosure by the Department...
Comparison of interventions to improve long-term medication adherence across different clinical conditions: A systematic review with network meta-analysis
Background: Medication non-adherence has a dynamic, temporal and multifactorial nature with a significant impact on economic and clinical outcomes. Interventions to improve adherence are complex and require adaptation to patients’...
Accuracy of anal cytology for diagnostic of precursor lesions of anal cancer: Systematic review and meta-analysis
BACKGROUND: Anal canal carcinoma is relevant because it commonly occurs in high-risk groups, and its incidence has been increasing. OBJECTIVE: This study evaluated the accuracy of anal cytology in the...
Prevalence of metabolic syndrome among HIV-positive and HIV-negative populations in sub-Saharan Africa – A systematic review and meta-analysis
BACKGROUND: Metabolic syndrome (MetS) is a constellation of conditions that increase the risk of cardiovascular diseases. It is an emerging concern in sub-Saharan African (SSA) countries, particularly because of an...
A systematic review of adherence to oral pre-exposure prophylaxis for HIV — How can we improve uptake and adherence?
INTRODUCTION: Oral pre-exposure prophylaxis (PrEP) is an effective strategy to reduce the risk of HIV transmission in high risk individuals. However, the effectiveness of oral pre-exposure prophylaxis is highly dependent...
Paediatric postdischarge mortality in developing countries: A systematic review
OBJECTIVES: To update the current evidence base on paediatric postdischarge mortality (PDM) in developing countries. Secondary objectives included an evaluation of risk factors, timing and location of PDM. DESIGN: Systematic...
Cost-effectiveness of HIV screening in high-income countries: A systematic review
INTRODUCTION: Over 2 million people in high-income countries live with HIV. Early diagnosis and treatment present benefits for infected subjects and reduce secondary transmissions. Cost-effectiveness analyses are important to effectively...