Category Archives: General HIV+ population

Reviews on HIV+ people where the population is not specified

HIV and human herpesvirus 8 co-infection across the globe: Systematic review and meta-analysis

2016

HIV-infection is an important risk factor for developing Kaposi sarcoma (KS), but it is unclear whether HIV-positive persons are also at increased risk of co-infection with human herpesvirus 8 (HHV-8),...

Depression in HIV infected patients: A review

2015

Depression is the most common neuropsychiatric complication in HIV-infected patients and may occur in all phases of the infection. Accurately, diagnosing major depressive disorder in the context of HIV is...

Expanding access to HIV viral load testing: A systematic review of RNA stability in EDTA tubes and PPT beyond current time and temperature thresholds

2014

BACKGROUND: HIV viral load (VL) testing is the gold standard for antiretroviral treatment monitoring, but many barriers exist to VL testing in resource-limited settings, including storage and transport limitations for...

The effects of RANTES polymorphisms on susceptibility to HIV-1 infection and disease progression: Evidence from an updated meta-analysis

2016

Associations of regulated on activation, normal T cell expressed and secreted (RANTES) -403G/A, -28C/G and In1.1T/C polymorphisms with HIV-1 infection and the progression of HIV-1 disease have been widely reported...

Interventions to promote adherence to antiretroviral therapy in Africa: A network meta-analysis

2014

BACKGROUND: Adherence to antiretroviral therapy (ART) is necessary for the improvement of the health of patients and for public health. We sought to determine the comparative effectiveness of different interventions...

A systematic review of treatment fatigue among HIV-infected patients prescribed antiretroviral therapy

2015

HIV treatment requires lifelong adherence to medication regimens that comprise inconvenient scheduling, adverse side effects, and lifestyle changes. Antiretroviral adherence and treatment fatigue have been inextricably linked. Adherence in HIV-infected...

System factors as correlates of medication adherence in transplant and HIV populations: A systematic review

2011

Purpose: Medication adherence (MA) is influenced not only by characteristics of the individual patient, but also by factors at the healthcare system level, i.e., micro- (e.g. healthcare worker, social support),...

Antiretroviral pharmacokinetic profile: A review of sex differences

2007

BACKGROUND: Emerging evidence suggests that female sex may be associated with increased risk of developing antiretroviral toxicities. Although the mechanisms of sex-related antiretroviral pharmacodynamic differences remain poorly understood and may...

Effectiveness of protease inhibitor monotherapy versus combination antiretroviral maintenance therapy: A meta-analysis

2011

BACKGROUND: The unparalleled success of combination antiretroviral therapy (cART) is based on the combination of three drugs from two classes. There is insufficient evidence whether simplification to ritonavir boosted protease...

Systematic review of the effectiveness of mass communication programs to change HIV/AIDS-related behaviors in developing countries

2006

This review systematically examined the effectiveness of 24 mass media interventions on changing human immunodeficiency virus (HIV)-related knowledge, attitudes and behaviors. The intervention studies were published from 1990 through 2004,...

Unstructured treatment interruption of antiretroviral therapy in clinical practice: A systematic review

2011

Objective To characterize the frequency, reasons, risk factors, and consequences of unstructured anti-retroviral treatment interruptions. Method Systematic review. Results Seventy studies were included. The median proportion of patients interrupting treatment...

Limited benefit of antiretroviral resistance testing in treatment-experienced patients: A meta-analysis

2004

OBJECTIVE: To estimate the effectiveness of resistance assessments based on viral sequencing (genotypic antiretroviral resistance testing, GART), phenotypic antiretroviral resistance testing (PART) or virtual PART (vPART) in the management of...

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