Category Archives: General HIV+ population
Reviews on HIV+ people where the population is not specified
Standard care quality determines treatment outcomes in control groups of HAART-adherence intervention studies: Implications for the interpretation and comparison of intervention effects.
Objective: Clinical trials of behavioral interventions seek to enhance evidence-based health care. However, in case the quality of standard care provided to control conditions varies between studies and affects outcomes,...
Patient support and education for promoting adherence to highly active antiretroviral therapy for HIV/AIDS
Background: Adherence to prescribed regimens is required to derive maximal benefit from many highly active antiretroviral therapy (HAART) regimens in people living with HIV/AIDS.Objectives: To conduct a systematic review of...
Effects of psychological interventions on neuroendocrine hormone regulation and immune status in HIV-positive persons: A review of randomized controlled trials
We reviewed randomized controlled trials (RCTs) that examined the effects of psychological interventions on HIV disease markers including neuroendocrine hormone regulation and immune status. Utilizing both PubMed and PsycINFO, we...
Sexual transmission of HIV according to viral load and antiretroviral therapy: Systematic review and meta-analysis
OBJECTIVES:: To synthesize the evidence on the risk of HIV transmission through unprotected sexual intercourse according to viral load and treatment with combination antiretroviral therapy (ART). DESIGN:: Systematic review and...
Posaconazole for the treatment of oropharyngeal candidiasis, including triazole-resistant disease, in HIV-positive patients
Oropharyngeal candidiasis is a common affliction in HIV-positive patients worldwide. Although the incidence has decreased with the advent of potent antiviral combinations, it continues to be a cause of significant...
Etravirine (TMC-125): The evidence for its place in the treatment of HIV-1 infection
Introduction: Etravirine is a novel nonnucleoside reverse transcriptase inhibitor (NNRTI) specifically designed to suppress the replication of viruses resistant to the three currently approved NNRTIs efavirenz, nevirapine, and delavirdine. Aims:...
Predictive value of interferon- release assays for incident active tuberculosis: A systematic review and meta-analysis
Background: We aimed to assess whether interferon- release assays (IGRAs) can predict the development of active tuberculosis and whether the predictive ability of these tests is better than that of...
The effectiveness of pneumococcal polysaccharide vaccines in adults: A systematic review of observational studies and comparison with results from randomised controlled trials
The use of pneumococcal polysaccharide vaccine has remained controversial since licensure, especially in the elderly. Observational studies form much of the evidence base. We conducted a systematic review of observational...
The effect of electronic medical record-based clinical decision support on HIV care in resource-constrained settings: A systematic review
Background: It is estimated that one million people infected with HIV initiate anti-retroviral therapy (ART) in resource-constrained countries annually. This occurs against a background of overburdened health workers with limited...
