Category Archives: General HIV+ population
Reviews on HIV+ people where the population is not specified
The effectiveness of HIV partner counseling and referral services in increasing identification of HIV-positive individuals: A systematic review
Partner counseling and referral services (PCRS) are part of the spectrum of care for HIV-positive people and their sexual or needle-sharing partners. Referral includes notifying partners of exposure, after which...
Improving the prevention, diagnosis and treatment of TB among people living with HIV: The role of operational research
Operational research is necessary to improve the access to and delivery of tuberculosis prevention, diagnosis and treatment interventions for people living with HIV. We conducted an extensive review of the...
Performance of commercial herpes simplex virus type-2 antibody tests using serum samples from Sub-Saharan Africa: A systematic review and meta-analysis
BACKGROUND: Several commercial type-specific serologic tests are available for herpes simplex virus type 2 (HSV-2). Poor specificity of some tests has been reported on samples from sub-Saharan Africa. METHODS: To...
Adherence to antiretroviral therapy in sub-Saharan Africa and North America: A meta-analysis
CONTEXT: Adherence to antiretroviral therapy is a powerful predictor of survival for individuals living with human immunodeficiency virus (HIV) and AIDS. Concerns about incomplete adherence among patients living in poverty...
Interventions for the treatment of decreased bone mineral density associated with HIV infection
BACKGROUND: Decreased bone mineral density (BMD) occurs more commonly in patients with HIV than in the general population, making this group more susceptible to fragility fractures. However, bone loss is...
Clinical efficacy of antiretroviral combination therapy based on protease inhibitors or non-nucleoside analogue reverse transcriptase inhibitors: Indirect comparison of controlled trials
Objective: To compare the clinical efficacy of triple antiretroviral regimens based on protease inhibitors and non-nucleoside analogue reverse transcriptase inhibitors (NNRTIs) in adults positive for antibodies to HIV-1. Design: Systematic...
Timing of antiretroviral therapy for HIV in the setting of TB treatment
The convergent human immunodeficiency virus (HIV) and tuberculosis (TB) pandemics continue to collectively exact significant morbidity and mortality worldwide. Highly active antiretroviral therapy (HAART) has been a critical component in...
Efficacy of selected treatments of HIV wasting: A systematic review and meta-analysis
PURPOSE: To assess the efficacy of recombinant human growth hormone (rhGH), testosterone, and anabolic steroids in the treatment of HIV wasting. METHODS: A systematic review and meta-analysis of studies published...
Antiretroviral adherence interventions in Southern Africa: Implications for using HIV treatments for prevention
There is concern that the expansion of ART (antiretroviral treatment) programmes to incorporate the use of treatment as prevention (TasP) may be associated with low levels of adherence and retention...
Nonoccupational postexposure prophylaxis following sexual assault in industrialized low-HIV-prevalence countries: A review
Although available for over a decade, use of nonoccupational postexposure prophylaxis (nPEP) remains controversial in the United States. There are concerns over sexual assault survivors’ adherence, or lack thereof, leading...
Terbinafine in the treatment of onychomycosis: A review of its efficacy in high-risk populations and in patients with nondermatophyte infections
BACKGROUND: The prevalence of onychomycosis is higher in certain high-risk populations, such as the immunocompromised, diabetics and human immunodeficiency virus (HIV)-positive patients. These patients can also develop onychomycosis due to...
