Category Archives: General HIV+ population
Reviews on HIV+ people where the population is not specified
Systematic review and meta-analysis of linkage to HIV care interventions in the United States, Canada, and Ukraine (2010–2021)
We conducted a systematic review and meta-analysis of interventions targeting linkage to HIV care in the US, Canada, and Europe. We searched six databases (PubMed, Embase, Cochrane Library, Web of...
A systematic review on cardiometabolic risks and perinatal outcomes among pregnant women living with HIV in the era of antiretroviral therapy
Antiretroviral therapy (ART) regimens have been shown to cause metabolic changes in people living with HIV (PLWH), predisposing them to cardiometabolic disease (CVMD). However, such evidence is less established in...
Adverse perinatal outcomes attributable to HIV in sub-Saharan Africa from 1990 to 2020: Systematic review and meta-analyses
Background: Maternal HIV infection and antiretroviral drugs (ARVs) are associated with increased risks of adverse perinatal outcomes. The vast majority of pregnant women living with HIV (WLHIV) reside in sub-Saharan Africa....
Safety and efficacy of long-acting injectable agents for HIV-1: Systematic review and meta-analysis
Background: HIV-1 infection continues to affect global health. Although antiretrovirals can reduce the viral load or prevent HIV-1 infection, current drugs require daily oral use with a high adherence level. Long-acting...
Global and regional estimate of HIV-associated stroke burden: A meta-analysis and population attributable modeling study
Background: This study aimed to determine the correlation between human-immunodeficiency-virus (HIV) infection and stroke, as well as to estimate the global, regional, and national burden of HIV-associated stroke. Methods: A registered meta-analysis...
Does engagement in HIV care affect screening, diagnosis, and control of noncommunicable diseases in sub-Saharan Africa? A systematic review and meta-analysis
OBJECTIVE: Low- and middle-income countries are facing a growing burden of noncommunicable diseases (NCDs). Providing HIV treatment may also provide opportunities to increase access to NCD services in under-resourced environments....
Multimodality imaging in HIV-associated cardiovascular complications: A comprehensive review
Human immunodeficiency virus (HIV) infection is a leading cause of mortality and morbidity worldwide. The introduction of antiretroviral therapy (ART) has significantly reduced the risk of developing acquired immune deficiency...
Tools for screening and measuring anxiety among women living with HIV of reproductive age: A scoping review
Emerging evidence suggests that women living with HIV (WLWH) may experience higher rates of anxiety than men living with HIV and women living without HIV. To date, relatively little knowledge...
Association between integrase strand transfer inhibitor use with insulin resistance and incident diabetes mellitus in persons living with HIV: A systematic review and meta-analysis
Whether integrase strand transfer inhibitors (INSTIs) are associated with a higher risk of incident type 2 diabetes mellitus (DM) than other antiretroviral therapies (ART) needs to be established. MEDLINE, Embase,...
Can contingency management solve the problem of adherence to antiretroviral therapy in drug-dependent individuals?
Drug misuse among people living with HIV (human immunodeficiency virus) is associated with higher mortality. It is a frequently observed reason for treatment abandonment, with people who misuse drugs showing...
Pharmacotherapeutic interventions in people living with HIV undergoing solid organ transplantation: A scoping review
The pharmacotherapeutic management of people living with HIV (PLWHIV) undergoing solid organ transplantation (SOT) is clinically challenging, mainly due to the frequent occurrence of complex drug-drug interactions. Although various strategies...
Association of apolipoprotein E epsilon 4 and cognitive impairment in adults living with human immunodeficiency virus: A meta-analysis
Background: It is controversial whether the apolipoprotein E epsilon 4 allele (APOE ε4) is a risk gene for human immunodeficiency virus (HIV)-related neurocognitive impairment. This meta-analysis aimed to summarize evidence of...