Category Archives: General HIV+ population
Reviews on HIV+ people where the population is not specified
Association between integrase strand transfer inhibitor use with insulin resistance and incident diabetes mellitus in persons living with HIV: A systematic review and meta-analysis
Whether integrase strand transfer inhibitors (INSTIs) are associated with a higher risk of incident type 2 diabetes mellitus (DM) than other antiretroviral therapies (ART) needs to be established. MEDLINE, Embase,...
Can contingency management solve the problem of adherence to antiretroviral therapy in drug-dependent individuals?
Drug misuse among people living with HIV (human immunodeficiency virus) is associated with higher mortality. It is a frequently observed reason for treatment abandonment, with people who misuse drugs showing...
Pharmacotherapeutic interventions in people living with HIV undergoing solid organ transplantation: A scoping review
The pharmacotherapeutic management of people living with HIV (PLWHIV) undergoing solid organ transplantation (SOT) is clinically challenging, mainly due to the frequent occurrence of complex drug-drug interactions. Although various strategies...
Association of apolipoprotein E epsilon 4 and cognitive impairment in adults living with human immunodeficiency virus: A meta-analysis
Background: It is controversial whether the apolipoprotein E epsilon 4 allele (APOE ε4) is a risk gene for human immunodeficiency virus (HIV)-related neurocognitive impairment. This meta-analysis aimed to summarize evidence of...
Adult HIV-1 incidence across 15 high-burden countries in sub-Saharan Africa from 2015 to 2019: A pooled analysis of nationally representative data
Background Harmonised population-based surveys with recent HIV-1 infection testing algorithms permit pooled cross-sectional estimation of HIV incidence across multiple countries. We aimed to estimate adult HIV-1 incidence rates and number...
Addressing the unmet mental health needs of people living with HIV: A scoping review of interventions in sub-Saharan Africa
ABSTRACTSome mental health interventions have addressed mental health among people living with HIV (PLWH) using a variety of approaches, but little is known about the details of such interventions in...
Efficacy, safety and tolerability of Biktarvy in HIV-1 infection: A scoping review
Background: Biktarvy is approved for use in HIV-1 infection in both treatment-naïve and treatment-experienced individuals, after a series of successful phase III trials. However, studies on real-world evidence on its efficacy,...
The interplay among HIV, monocytes/macrophages, and extracellular vesicles: A systematic review
Despite effective antiretroviral therapies, chronic inflammation and spontaneous viral “blips” occur in HIV-infected patients. Given the roles for monocytes/macrophages in HIV pathogenesis and extracellular vesicles in intercellular communication, we performed...
Effectiveness of behavioural economics informed interventions for the prevention, screening, and antiretroviral treatment of HIV infection: A systematic review of randomized controlled trials
Failure to meet international targets set for the human immunodeficiency virus HIV pandemic suggests that more effective public health strategies are needed. New strategies informed by behavioural economics are now...
Performances of Dried Blood Spots and Point-of-Care Devices to Identify Virological Failure in HIV-Infected Patients: A Systematic Review and Meta-Analysis
To broaden access to HIV viral load monitoring (VLM), the use of blood samples from dried blood spots (DBS) or point-of-care (POC) devices, could be of great help in settings...
Prevalence of human immunodeficiency virus (HIV) among pregnant women in Nigeria: A systematic review and meta-analysis
Objective To estimate prevalence of HIV infection in Nigeria and to examine variations by geopolitical zones and study characteristics to inform policy, practice and research. Methods We conducted a comprehensive search of...
