Category Archives: Other
Reviews that are lab-based (e.g. genes, pharmaceuticals) or on unique groups of people (e.g. fishermen, nurses)
Pharmacogenetic considerations for HIV treatment in different ethnicities: An update
INTRODUCTION: Variations in the human genome sequence sometimes play an important role in pharmacokinetics and/or pharmacodynamics. Previous studies have demonstrated a high degree of variation both between and within different...
Changing the culture of neurodisability through language and sensitivity of providers: Creating a safe place for LGBTQIA+ people
BACKGROUND: There is an increasing interest in sexual and gender diversity in neurorehabilitation. Healthcare professionals wanting to improve their practice know the importance of understanding the needs and expectations of...
Risk of developing antiphospholipid antibodies following viral infection: A systematic review and meta-analysis
Objective The objective of this paper is to conduct a systematic review and meta-analysis on the risk of developing elevated antiphospholipid (aPL) antibodies and related thromboembolic and/or pregnancy events following...
To err is human, to correct is public health: A systematic review examining poor quality testing and misdiagnosis of HIV status
INTRODUCTION: In accordance with global testing and treatment targets, many countries are seeking ways to reach the “90-90-90” goals, starting with diagnosing 90% of all people with HIV. Quality HIV...
Ranking 93 health interventions for low- and middle-income countries by cost-effectiveness
BACKGROUND: Cost-effectiveness rankings of health interventions are useful inputs for national healthcare planning and budgeting. Previous comprehensive rankings for low- and middle- income countries were undertaken in 2005 and 2006,...
Specification of implementation interventions to address the cascade of HIV care and treatment in resource-limited settings: A systematic review
BACKGROUND: The global response to HIV has started over 18 million persons on life-saving antiretroviral therapy (ART)-the vast majority in low- and middle-income countries (LMIC)-yet substantial gaps remain: up to...
Status and methodology of publicly available national HIV care continua and 90-90-90 targets: A systematic review
BACKGROUND: In 2014, the Joint United Nations Program on HIV/AIDS (UNAIDS) issued treatment goals for human immunodeficiency virus (HIV). The 90-90-90 target specifies that by 2020, 90% of individuals living...
Performance of point-of-care CD4 testing technologies in resource-constrained settings: A systematic review and meta-analysis
BACKGROUND: Point-of-care (POC) CD4 testing increases patient accessibility to assessment of antiretroviral therapy eligibility. This review evaluates field performance in low and middle-income countries (LMICs) of currently available POC CD4...
Critical review: What dose of rifabutin is recommended with antiretroviral therapy?
Since the advent of combination antiretroviral therapy to successfully treat HIV infection, drug-drug interactions (DDIs) have become a significant problem as many antiretrovirals (ARVs) are metabolized in the liver. Antituberculous...
