Category Archives: Other

Reviews that are lab-based (e.g. genes, pharmaceuticals) or on unique groups of people (e.g. fishermen, nurses)

Incidence and prevalence of type 2 diabetes mellitus with HIV infection in Africa: A systematic review and meta-analysis

2017

OBJECTIVES: This systematic review aims to investigate the incidence and prevalence of type 2 diabetes mellitus (T2DM) in patients with HIV infection in African populations. SETTING: Only studies reporting data...

Safety of tenofovir disoproxil fumarate-based antiretroviral therapy regimens in pregnancy for HIV-infected women and their infants: A systematic review and meta-analysis

2017

BACKGROUND: There are limited data on adverse effects of tenofovir disoproxil fumarate (TDF)-based antiretroviral therapy (ART) on pregnant women and their infants. METHODS: We conducted a systematic review of studies...

A systematic review of cardiovascular disease in sexual minorities

2017

BACKGROUND: Mental health and HIV disparities are well documented among sexual minorities, but there is a dearth of research on other chronic conditions. Cardiovascular disease remains the leading cause of...

Economic impact of routine opt-out antenatal HIV screening: A systematic review

2017

OBJECTIVES: To evaluate the economic impact of routine testing of HIV in antenatal (ANC) settings. BACKGROUND: Many children are being infected with HIV through mother to child transmission (MTCT) of...

Association between systemic diseases and endodontic outcome: A systematic review

2017

INTRODUCTION: To date, the relationships between systemic diseases and endodontic treatment outcomes remain poorly studied. Thus, the purpose of this systematic review was to evaluate the relationship between host-modifying factors...

The impact of sharps injuries on student nurses: A systematic review

2016

AIMS AND OBJECTIVES: The purpose of this review was to discover the impact of sharps injuries in the student nurse population. BACKGROUND: Much is known and reported about sharps injuries...

The dynamic role of the IL-33/ST2 axis in chronic viral-infections: Alarming and adjuvanting the immune response

2016

UNLABELLED: Interleukin 33 (IL-33), a member of the IL-1 family, is constitutively expressed in epithelial and in endothelial cells at barrier sites, acting as a danger signal and adjuvanting the...

Deploying aptameric sensing technology for rapid pandemic monitoring

2015

The genome of virulent strains may possess the ability to mutate by means of antigenic shift and/or antigenic drift as well as being resistant to antibiotics with time. The outbreak...

A review of single-tablet regimens for the treatment of HIV-1 infection

2017

OBJECTIVE: To review the pharmacokinetics, safety, drug-drug interactions, and advantages and disadvantages of currently available single-tablet regimens (STRs) for HIV-1 infection. DATA SOURCES: A search using PubMed was conducted (up...

A comprehensive review of the barriers and promoters health workers experience in delivering prevention of vertical transmission of HIV services in sub-Saharan Africa

2016

Despite significant biomedical and policy advances, 199,000 infants and young children in sub-Saharan Africa (SSA) became infected with HIV in 2013, indicating challenges to implementation of these advances. To understand...

Conceptualizing care continua: Lessons from HIV, hepatitis C virus, tuberculosis and implications for the development of improved care and prevention continua

2017

BACKGROUND: To examine the application of continuum models to tuberculosis, HIV, and other conditions; to theorize the concept of continua; and to learn lessons that could inform the development of...

The HIV-1 vpr protein: A multifaceted target for therapeutic intervention

2017

The human immunodeficiency virus type 1 (HIV-1) Vpr protein is an attractive target for antiretroviral drug development. The conservation both of the structure along virus evolution and the amino acid...

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