Category Archives: Treatment
Discontinuation from antiretroviral therapy: A continuing challenge among adults in HIV care in Ethiopia: A systematic review and meta-analysis
BACKGROUND: Discontinuation of antiretroviral therapy (ART) reduces the immunological benefit of treatment and increases complications related to human immune-deficiency virus (HIV). However, the risk factors for ART discontinuation are poorly...
What is the relationship between increased access to HAART, relationship status and fertility decisions amongst HIV positive women? A literature review and meta-analysis
AIMS AND OBJECTIVES: To investigate the relationship between fertility decisions, to have already had a child or to desire to have one in the future, and the prognostic factors of;...
Toxoplasmic encephalitis relapse rates with pyrimethamine-based therapy: Systematic review and meta-analysis
Toxoplasmic encephalitis (TE) is caused by Toxoplasma gondii infection and can be a life-threatening disease in immunocompromised patients. This study evaluated the rate of relapse associated with pyrimethamine-based maintenance therapy...
PET brain imaging in HIV-associated neurocognitive disorders (HAND) in the era of combination antiretroviral therapy
Effective combination antiretroviral therapy (cART) has lead to a significant reduction in the prevalence and incidence of central nervous system (CNS) HIV-associated brain disease, particularly CNS opportunistic infections and HIV...
Marked sex differences in all-cause mortality on antiretroviral therapy in low- and middle-income countries: A systematic review and meta-analysis
INTRODUCTION: While women and girls are disproportionately at risk of HIV acquisition, particularly in low- and middle-income countries (LMIC), globally men and women comprise similar proportions of people living with...
Alarming increase in pretreatment HIV drug resistance in children living in sub-Saharan Africa: A systematic review and meta-analysis
BACKGROUND: Children have an augmented risk of pretreatment HIV drug resistance (PDR) due to exposure to antiretroviral drugs for the prevention of mother-to-child transmission (PMTCT). Paediatric data are essential to...
Motivations and barriers to treatment uptake and adherence among people living with HIV in Australia: A mixed-methods systematic review
In Australia, approximately 30% of people diagnosed with HIV are not accessing treatment and 8% of those receiving treatment fail to achieve viral suppression. Barriers limiting effective care warrant further...
HIV care and treatment experiences among female sex workers living with HIV in sub-Saharan Africa: A systematic review
Female sex workers (FSW) living with HIV in sub-Saharan Africa have poor engagement to HIV care and treatment. Understanding the HIV care and treatment engagement experiences of FSW has important...
