Category Archives: Treatment
Nucleoside reverse transcriptase inhibitor-reducing strategies in HIV treatment: Assessing the evidence
Antiretroviral (ARV) therapy, comprising a backbone of two nucleos(t)ide reverse transcriptase inhibitors (NRTIs) plus another ARV, is the recognized standard of care (SOC), which has helped extend life expectancy in...
Integration of sexually transmitted infection (STI) services into HIV care and treatment services for women living with HIV: A systematic review
OBJECTIVE: To review and critically appraise the existing evidence on integration of sexually transmitted infection (STI) services into HIV care and treatment services for women living with HIV. DESIGN: Systematic...
Exploring ‘generative mechanisms’ of the antiretroviral adherence club intervention using the realist approach: A scoping review of research-based antiretroviral treatment adherence theories
BACKGROUND: Poor retention in care and non-adherence to antiretroviral therapy (ART) continue to undermine the success of HIV treatment and care programmes across the world. There is a growing recognition...
The impact of motivational interviewing on adherence and symptom severity in adolescents and young adults with chronic illness: A systematic review
OBJECTIVE: Given the negative consequences associated with non-adherence in adolescents and young adults (AYAs) with chronic illness, it is important to identify interventions to address this issue. Therefore, this review’s...
Are religion and spirituality barriers or facilitators to treatment for HIV: A systematic review of the literature
Much attention has been given to the relationship between religion/spirituality (R/S) and HIV in recent years, but comparatively little has been explored in regard to R/S and HIV testing, retention...
The association between HIV (treatment), pregnancy serum lipid concentrations and pregnancy outcomes: A systematic review
BACKGROUND: Observed adverse effects of antiretroviral therapy (ART) on the lipid profile could be of significance in pregnancy. This systematic review aims to summarize studies that investigated the association between...
Reliability of white matter microstructural changes in HIV infection: Meta-analysis and confirmation
BACKGROUND: Diffusion tensor imaging has been widely used to measure HIV effects on white matter microarchitecture. While many authors have reported reduced fractional anisotropy and increased mean diffusivity in HIV,...
Examining the health and health service utilization of heterosexual men with HIV: A community-informed scoping review
The prevalence of HIV infection among heterosexual men has increased. Consequently, the need for health and support services for this group is likely to increase. We conducted a scoping review...
Social and behavioral interventions for improving quality of life of HIV infected people receiving antiretroviral therapy: A systematic review and meta-analysis
BACKGROUND: Improvement in quality of life is crucial for HIV infected people. Social and behavioral interventions have been implemented in different contexts to improve the quality of life among HIV...
The impact of cannabis and cannabinoids for medical conditions on health-related quality of life: A systematic review and meta-analysis
INTRODUCTION: The use of cannabis or cannabinoids to treat medical conditions and/or alleviate symptoms is increasingly common. However, the impact of this use on patient reported outcomes, such as health-related...
Is there sufficient evidence for a causal association between antiretroviral therapy and diabetes in HIV-infected patients? A meta-analysis
BACKGROUND: The association of antiretroviral therapy (ART) with diabetes is inconsistent and varies widely across primary epidemiological studies. A comprehensive and more precise estimate of this association is fundamental to...
