Category Archives: Treatment
Objective impairments of gait and balance in adults living with HIV-1 infection: A systematic review and meta-analysis of observational studies
BACKGROUND: Gait and balance deficits are reported in adults with HIV infection and are associated with reduced quality of life. Current research suggests an increased fall-incidence in this population, with...
Efficacy and tolerability of tenofovir disoproxil fumarate based regimen as compared to zidovudine based regimens: A systematic review and meta-analysis
BACKGROUND: Although tenofovir (TDF)/emtricitabine (FTC)/efavirenz (EFV) and zidovudine (ZDV)/lamivudine (3TC)/efavirenz (EFV) are used as preferred first line regimen, their head-to-head comparison in terms of their efficacy and tolerability was limited....
HIV programs in Iran (Persia), Iraq and Saudi Arabia: A brief review of current evidence in West and Southwest Asia
BACKGROUND: In Western and Southwest Asia, literature is not documented on human immunodeficiency virus (HIV) programs in Iran, Iraq and Saudi Arabia. The present study is the first brief review...
Nucleoside reverse transcriptase inhibitor-reducing strategies in HIV treatment: Assessing the evidence
Antiretroviral (ARV) therapy, comprising a backbone of two nucleos(t)ide reverse transcriptase inhibitors (NRTIs) plus another ARV, is the recognized standard of care (SOC), which has helped extend life expectancy in...
Integration of sexually transmitted infection (STI) services into HIV care and treatment services for women living with HIV: A systematic review
OBJECTIVE: To review and critically appraise the existing evidence on integration of sexually transmitted infection (STI) services into HIV care and treatment services for women living with HIV. DESIGN: Systematic...
Exploring ‘generative mechanisms’ of the antiretroviral adherence club intervention using the realist approach: A scoping review of research-based antiretroviral treatment adherence theories
BACKGROUND: Poor retention in care and non-adherence to antiretroviral therapy (ART) continue to undermine the success of HIV treatment and care programmes across the world. There is a growing recognition...
The impact of motivational interviewing on adherence and symptom severity in adolescents and young adults with chronic illness: A systematic review
OBJECTIVE: Given the negative consequences associated with non-adherence in adolescents and young adults (AYAs) with chronic illness, it is important to identify interventions to address this issue. Therefore, this review’s...
Are religion and spirituality barriers or facilitators to treatment for HIV: A systematic review of the literature
Much attention has been given to the relationship between religion/spirituality (R/S) and HIV in recent years, but comparatively little has been explored in regard to R/S and HIV testing, retention...
Association between depression and antiretroviral therapy use among people living with HIV: A meta-analysis
Depression is common among people living with HIV (PLHIV). Studies on the relationship between depression and use of antiretroviral therapy (ART) are inconclusive. A meta-analysis was conducted to summarize the...
Physical activity correlates in people living with HIV/AIDS: A systematic review of 45 studies
PURPOSE: Understanding barriers and facilitators of physical activity participation in persons living with HIV/AIDS is an essential first step in order to devise effective interventions. The present review provides a...
Social and behavioral interventions for improving quality of life of HIV infected people receiving antiretroviral therapy: A systematic review and meta-analysis
BACKGROUND: Improvement in quality of life is crucial for HIV infected people. Social and behavioral interventions have been implemented in different contexts to improve the quality of life among HIV...
