Category Archives: Treatment

Impact of ART on the fertility of HIV-positive women in sub-Saharan Africa

2016

OBJECTIVE: Understanding the fertility of HIV-positive women is critical to estimating HIV epidemic trends from surveillance data and to planning resource needs and coverage of prevention of mother-to-child transmission services...

Surveillance of HIV transmitted drug resistance in Latin America and the Caribbean: A systematic review and meta-analysis

2016

BACKGROUND: HIV transmitted drug resistance (TDR) remains at moderate level in Latin America and the Caribbean (LAC). However, different epidemiologic scenarios could influence national and sub-regional TDR levels and trends....

Beyond the pap smear: Gender-responsive HIV care for women

2016

Women comprise nearly one-quarter of all people living with human immunodeficiency virus (HIV) in the U.S. and 20 percent of incident annual cases. Though women overall are more likely than...

Impact of opioid substitution therapy on antiretroviral therapy outcomes: A systematic review and meta-analysis

2016

BACKGROUND: Human immunodeficiency virus (HIV)-infected people who inject drugs (PWID) frequently encounter barriers accessing and remaining on antiretroviral therapy (ART). Some studies have suggested that opioid substitution therapy (OST) could...

Efficacy and safety of contemporary dual-drug antiretroviral regimens as first-line treatment or as a simplification strategy: A systematic review and meta-analysis

2016

BACKGROUND: Some guidelines recommended two-drug antiretroviral therapies as alternative regimens to triple therapy in selected patients with the aim of reducing drug burden and toxicity and preserving future treatment options....

Information and communication technologies for adherence to antiretroviral treatment in adults with HIV/AIDS

2016

INTRODUCTION: Information and communication technologies support interventions directed at the prevention of HIV transmission and patient monitoring by promoting improved accessibility and quality of care. OBJECTIVE: To evaluate the efficacy...

Adverse-drug-reaction-related hospitalisations in developed and developing countries: A review of prevalence and contributing factors

2016

Adverse drug reactions (ADRs) are one of the leading causes of hospital admissions and morbidity in developed countries and represent a substantial burden on healthcare delivery systems. However, there is...

Retention of HIV-infected children in the first 12 months of anti-retroviral therapy and predictors of attrition in resource limited settings: A systematic review

2016

Current UNAIDS goals aimed to end the AIDS epidemic set out to ensure that 90% of all people living with HIV know their status, 90% initiate and continue life-long anti-retroviral...

Body fat changes in people living with HIV on antiretroviral therapy

2016

Although more than one in two HIV-infected persons may develop central fat accumulation soon after commencing antiretroviral therapy, the association between antiretroviral therapy and body fat changes has not been...

Effectiveness and safety of oral HIV preexposure prophylaxis for all populations

2016

OBJECTIVE: Preexposure prophylaxis (PrEP) offers a promising new approach to HIV prevention. This systematic review and meta-analysis evaluated the evidence for use of oral PrEP containing tenofovir disoproxil fumarate as...

Genetic markers of the host in persons living with HTLV-1, HIV and HCV infections

2016

Human T-cell leukemia virus type 1 (HTLV-1), hepatitis C virus (HCV) and human immunodeficiency virus type 1 (HIV-1) are prevalent worldwide, and share similar means of transmission. These infections may...

Improving engagement in the HIV care cascade: A systematic review of interventions involving people living with HIV/AIDS as peers

2016

Improving patient engagement in HIV care is critical for maximizing the impact of antiretroviral therapy (ART). We conducted a systematic review of studies that used HIV-positive peers to bolster linkage,...

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