Category Archives: Treatment

More than 20 years of research into the quality of life of people with HIV and AIDS–a descriptive review of study characteristics and methodological approaches of published empirical studies

2013

BACKGROUND: The quality of life of people living with HIV and AIDS (PLWHA) is becoming increasingly important–a fact that is also reflected in extensive research efforts. Owing to the almost...

Use of antiretroviral therapy in pregnant HIV-infected women and the risk of premature delivery: A meta-analysis

2007

BACKGROUND: The use of antiretroviral agents in pregnant HIV-infected women has been reported to increase the risk of premature delivery in some studies. We performed a meta-analysis on relevant studies...

A systematic review of the impact of alcohol use disorders on HIV treatment outcomes, adherence to antiretroviral therapy and health care utilization

2010

BACKGROUND: Alcohol use disorders (AUDs) are highly prevalent and associated with non-adherence to antiretroviral therapy, decreased health care utilization and poor HIV treatment outcomes among HIV-infected individuals. OBJECTIVES: To systematically...

Neurocognitive impairment in HIV-1-infected adults in Sub-Saharan Africa: A systematic review and meta-analysis

2013

OBJECTIVE: To estimate the burden of HIV neurocognitive impairment (NCI) among adult patients on and off antiretroviral therapy (ART) in Sub-Saharan Africa. METHODS: Estimates were derived from a random effects...

Suppression of HBV by tenofovir in HBV/HIV coinfected patients: A systematic review and meta-analysis.

2013

BACKGROUND: Hepatitis B coinfection is common in HIV-positive individuals and as antiretroviral therapy has made death due to AIDS less common, hepatitis has become increasingly important. Several drugs are available...

A systematic review of pediatric adherence to antiretroviral therapy in low- and middle-income countries

2008

BACKGROUND: Sustaining antiretroviral therapy (ART) adherence requires accurate, consistent monitoring, a particular challenge for low-income countries. The optimal strategy to measure pediatric adherence remains unclear. OBJECTIVE: To conduct a systematic...

Sex differences in adherence to highly active antiretroviral therapy: A meta-analysis

2012

Observational studies have found that women tend to have lower adherence to highly active antiretroviral therapy (HAART) than men do, though no meta-analysis has yet investigated this trend. The aims...

Efficacy of influenza vaccination in HIV-positive patients: A systematic review and meta-analysis

2008

BACKGROUND: International treatment guidelines recommend that HIV-positive patients be vaccinated for influenza annually. Evidence supporting this recommendation is limited. We assessed the efficacy of influenza vaccines in preventing influenza in...

Vertically acquired paediatric HIV infection: the challenges of providing comprehensive packages of care in resource-limited settings

2008

The successes achieved in paediatric disease management in well-resourced countries in recent years highlight the vast divide between the care options, and ultimately survival, between developed and developing areas of...

HIV and HIV treatment: effects on fats, glucose and lipids

2007

BACKGROUND: Since the advent of effective antiretroviral therapy, infection with the human immunodeficiency virus has been transformed, in the Western world, to a chronic disease associated with a variety of...

Telephone delivered interventions for reducing morbidity and mortality in people with HIV infection

2013

Background: This is one of three Cochrane reviews examining the role of the telephone in HIV/AIDS services. Telephone interventions, delivered either by landline or mobile phone, may be useful in...

Efficacy and tolerability of initial antiretroviral therapy: A systematic review

2009

OBJECTIVES: Successful antiretroviral therapy (ART) is largely attributed to the type of third drug. Guidelines recommend regimens without systematic review of all factors that might affect treatment success, such as...

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