Category Archives: Treatment

Persistent difficulties in switching to second-line ART in sub-saharan Africa — A systematic review and meta-analysis

2013

OBJECTIVES: Switching to second-line antiretroviral therapy (ART) largely depends on careful clinical assessment and access to biological measurements. We performed a systematic review and meta-analysis to estimate the incidence of...

Immediate versus deferred zidovudine (AZT) in asymptomatic or mildly symptomatic HIV infected adults

2002

BACKGROUND: Zidovudine (AZT) monotherapy was the first antiretroviral drug to be tested widely. Subsequent trials in asymptomatic or early symptomatic HIV infection indicated short-term delays in disease progression with AZT,...

Antidepressants for neuropathic pain

2007

Background: This is an updated version of the original Cochrane review published in Issue 3, 2005 of The Cochrane Library . For many years antidepressant drugs have been used to...

Cardiac biomarkers in persons with HIV infection: A review of the literature

2014

No abstract.

Immunological and virological benefits resulted from short-course treatment during primary HIV infection: A meta-analysis

2013

OBJECTIVES: To assess the potential immunological and virological effects that result from short-course antiretroviral treatment during primary HIV infection (PHI). And to investigate whether treatment initiation time, treatment duration and...

Trichomoniasis and HIV interactions: A review

2013

OBJECTIVE: To discuss the epidemiology of Trichomonas vaginalis (TV) and HIV co-infections, the role of TV in acquisition and transmission of HIV, special treatment considerations for TV among women with...

Smoking-cessation interventions in people living with HIV infection: A systematic review

2013

Tobacco smoking remains a prevalent behavior in people living with HIV infection (PLWHs) and is associated with impaired immune functioning, increased cardiovascular risk, and decreased response to antiretroviral therapy. This...

The impact of participation in performing arts on adolescent health and behaviour: A systematic review of the literature

2008

This article reports a systematic review of literature published between 1994 and 2004 on the effects of performing arts for health in young people aged 11-18. The review includes research...

Unit costs for delivery of antiretroviral treatment and prevention of mother-to-child transmission of HIV: A systematic review for low- and middle-income countries

2011

As antiretroviral treatment (ART) for HIV/AIDS is scaled up globally, information on per-person costs is critical to improve efficiency in service delivery and to maximize coverage and health impact. The...

Social and structural factors associated with HIV disease progression among illicit drug users: A systematic review

2012

OBJECTIVE: To systematically review factors associated with HIV disease progression among illicit drug users, focusing on exposures exogenous to individuals that likely shape access and adherence to HIV treatment. DESIGN:...

High mortality amongst adolescents and adults with bacterial meningitis in sub-Saharan Africa: An analysis of 715 cases from Malawi

2013

Mortality from bacterial meningitis in African adults is significantly higher than those in better resourced settings and adjunctive therapeutic interventions such as dexamethasone and glycerol have been shown to be...

Monoclonal CCR5 antibody for treatment of people with HIV infection

2010

BACKGROUND: A monoclonal CCR5 antibody, PRO 140 (a humanised form of the PA14 antibody), inhibits CCR5-tropic (R5) HIV-1. This may be an effective new treatment for HIV-infected patients, with the...

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