Category Archives: Treatment

The Impact of DSM-IV Mental Disorders on Adherence to Combination Antiretroviral Therapy Among Adult Persons Living with HIV/AIDS: A Systematic Review

2012

This is a systematic review of eighty-two published studies investigating the impact of DSM-IV mental disorders on combination antiretroviral therapy (cART) adherence and persistence among persons living with HIV/AIDS (PLWHA)....

A systematic review and meta-regression of temporal trends in adult CD4(+) cell count at presentation to HIV care, 1992-2011

2013

Background. The clinical status of human immunodeficiency virus (HIV)-positive persons at the time of presentation to medical care has important individual- and population-level implications. Methods. We synthesized the literature on...

Monoclonal CCR5 antibody for treatment of people with HIV infection

2010

BACKGROUND: A monoclonal CCR5 antibody, PRO 140 (a humanised form of the PA14 antibody), inhibits CCR5-tropic (R5) HIV-1. This may be an effective new treatment for HIV-infected patients, with the...

Adherence-enhancing interventions for highly active antiretroviral therapy in HIV-infected patients — A systematic review

2013

OBJECTIVES: The objective of this systematic review was to evaluate the effectiveness of adherence-enhancing interventions for highly active antiretroviral therapy (HAART) in HIV-infected patients in developed countries. METHODS: A systematic...

Levels of salivary IgA antibodies to Candida spp. in HIV-infected adult patients: A systematic review

2010

Objective: To perform a systematic review of published data with the aim of evaluating the levels of IgA antibodies to Candida albicans in HIV-infected adult patients. Methods: The search strategy...

HIV prevention, treatment, and care services for people who inject drugs: A systematic review of global, regional, and national coverage

2010

Background: Previous reviews have examined the existence of HIV prevention, treatment, and care services for injecting drug users (IDUs) worldwide, but they did not quantify the scale of coverage. We...

Treatment of active tuberculosis in HIV-coinfected patients: A systematic review and meta-analysis

2010

BACKGROUND: Patients with human immunodeficiency virus (HIV) infection and tuberculosis have an increased risk of death, treatment failure, and relapse. METHODS: A systematic review and meta-analysis of randomized, controlled trials...

Effects of HIV antiretrovirals on the pharmacokinetics of hormonal contraceptives

2008

OBJECTIVES: To review available information on pharmacokinetic effects of HIV antiretrovirals on hormonal contraceptives. METHODS: A PubMed search was conducted from 1964 to 2006 using each antiretroviral generic name and...

Provider training and experience for people living with HIV/AIDS

2011

BACKGROUND: The complexity of HIV/AIDS raises challenges for the effective delivery of care. It is important to ensure that the expertise and experience of care providers is of high quality....

Economic and quality of life outcomes of antiretroviral therapy for HIV/AIDS in developing countries: A systematic literature review

2009

The impacts of antiretroviral therapy (ART) on quality of life, mental health, labor productivity, and economic wellbeing for people living with HIV/AIDS in developing countries are only beginning to be...

Nonnucleoside reverse transcriptase inhibitor resistance and the role of the second-generation agents

2010

OBJECTIVE: To review the current state of nonnucleoside reverse transcriptase inhibitor (NNRTI) resistance, discuss the promising role of second-generation NNRTIs, and provide insight into their clinical utility. DATA SOURCES: Articles...

Contraception for the HIV-positive woman: A review of interactions between hormonal contraception and antiretroviral therapy

2012

Background. Preventing unintended pregnancy in HIV-positive women can significantly reduce maternal-to-child HIV transmission as well as improve the woman’s overall health. Hormonal contraceptives are safe and effective means to avoid...

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