Category Archives: Treatment
A scoping review of methods used to assess medication adherence in patients with chronic conditions
BACKGROUND: Medication nonadherence of patients with chronic conditions is a complex phenomenon contributing to increased economic burden and decreased quality of life. Intervention development relies on accurately assessing adherence but...
Low-level viraemia: An emerging concern among people living with HIV in Uganda and across sub-Saharan Africa
Attaining viral load (VL) suppression for over 95% of the people living with HIV on antiretroviral therapy is a fundamental step in enabling Uganda and other sub-Saharan African countries to...
Effect of social support interventions on adherence to antiretroviral therapy among people living with HIV: A systematic review and meta-analysis
This systematic review and meta-analysis examined the effects of social support interventions (SSIs) on adherence to antiretroviral therapy (ART) among people living with HIV. We systematically searched Web of Science,...
First line antiretroviral treatment failure and its association with drug substitution and sex among children in Ethiopia: Systematic review and meta-analysis
Antiretroviral Treatment (ART) has significantly decreased HIV-related morbidity and mortality among children despite the issue of drug resistance and subsequent treatment failure appearing as a challenge. Different studies have been...
Effectiveness and safety of statins on outcomes in patients with HIV infection: A systematic review and meta-analysis
Statins are hypolipidaemic in human immunodeficiency virus (HIV) positive individuals. However, their effect on all-cause mortality and rate of discontinuation is unclear. We conducted a systematic review to evaluate the...
Barriers to uptake of long-acting antiretroviral products for treatment and prevention of human immunodeficiency virus (HIV) in high-income countries
Long-acting injectable antiretroviral therapy (LAI-ART) for the treatment and prevention of human immunodeficiency virus (HIV) holds great potential to shift treatment paradigms by offering an alternative to daily oral medication....
Review of antiretroviral therapy coverage in 10 highest burden HIV countries in Africa: 2015–2020
Africa is responsible for two-thirds of the global total of new HIV infections. South Africa, Nigeria, Mozambique, Uganda, Tanzania, Zambia, Zimbabwe, Kenya, Malawi, and Ethiopia were responsible for 80% of...
Antiretroviral drugs for treatment and prevention of HIV infection in adults: 2022 Recommendations of the International Antiviral Society-USA Panel
IMPORTANCE: Recent advances in treatment and prevention of HIV warrant updated recommendations to guide optimal practice. OBJECTIVE: Based on a critical evaluation of new data, to provide clinicians with recommendations...
Barriers and facilitators to the implementation and scale up of differentiated service delivery models for HIV treatment in Africa: A scoping review
BACKGROUND: In the face of health-system constraints, local policymakers and decision-makers face difficult choices about how to implement, expand and institutionalize antiretroviral therapy (ART) services. This scoping review aimed to...
Transition interventions for adolescents on antiretroviral therapy on transfer from pediatric to adult healthcare: A systematic review
Globally, adolescents living with HIV (ALHIV) experience poor health outcomes such as low retention in care, ART non-adherence and viral non-suppression. These outcomes coincide with the period during and after...
Body image in children and adolescents diagnosed with the human immunodeficiency virus: A systematic review
CONTEXT: The relationship with body image, which is the way the body presents itself to each subject, can be aggravated in children and adolescents diagnosed with an human immunodeficiency virus...
