Category Archives: Treatment
Prevalence and associated factors of treatment failure among children on ART in Ethiopia: A systematic review and meta-analysis
BACKGROUND: As the use of antiretroviral therapy (ART) increases, the issue of treatment failure is still a global challenge, particularly in a resource limited settings including Ethiopia. The results of...
Key population perceptions and opinions about long-acting antiretrovirals for prevention and treatment: A scoping review
Purpose of review: Key populations are disproportionately affected by human immunodeficiency virus (HIV). Access, retention, and adherence are important barriers for the efficacy of preexposure prophylaxis (PrEP) and HIV treatment among...
Traditional Chinese medicine for HIV-associated acute herpes zoster: A systematic review and meta-analysis of randomized trials
Background: Herpes zoster (HZ) is a common infection in individuals with acquired immunodeficiency syndrome (AIDS) patients. Traditional Chinese medicine (TCM) has been used widely in clinical practice for HZ, which remains...
Influence of combination antiretroviral therapy on HIV-1 serological responses and their implications: A systematic review and meta-analysis
We aimed to analyze HIV-1 seroreversion caused by combination antiretroviral therapy (cART) and to explore antibody levels of anti-HIV-1 as an alternative biomarker of HIV-1 reservoir. We searched PubMed, Embase,...
Mobile applications in HIV self-management: A systematic review of scientific literature
Self-management through mHealth by mobile apps creates new opportunities for people living with HIV (PLHIV) for integrated and accurate management. Our study focused on current evidence on HIV selfmanagement mobile...
A meta-analytic review of the effect of antiretroviral therapy on neurocognitive outcomes in adults living with HIV-1 in low-and middle-income countries
HIV-associated neurocognitive impairment remains a challenge even in the era of antiretroviral therapy (ART). Over 90% of people living with HIV are in low- and middle-income countries. Hence, it is...
Clinical and laboratory outcomes in HIV-1 and HTLV-1/2 coinfection: A systematic review
Aim: To perform a systematic review to describe the available findings on clinical outcomes in HIV-1 and HTLV-1/HTLV-2 co-infected individuals since 1995. Design: This Systematic Review used PECO criteria follow by PRISMA...
Impact of HIV-associated cognitive impairment on functional independence, frailty and quality of life in the modern era: A meta-analysis
HIV-associated neurocognitive disorder (HAND) is an important sequela of HIV infection. Combined antiretroviral therapy (cART) has improved the health outcomes of many people living with HIV but has given rise...
A systematic review and meta-analysis on depression and associated factors among adult HIV/AIDS-positive patients attending ART clinics of Ethiopia: 2021
INTRODUCTION: Depression is the most common mental health problem in people living with the human immune virus. It ranges from 11% to 63% in low- and middle-income countries. Depression was...
A critical review of symptom management nursing science on HIV-related fatigue and sleep disturbance
Despite improved antiretroviral treatments, people living with HIV (PLWH) continue to suffer from HIV-related fatigue and sleep disturbances. We first reviewed the definition, etiology, and research breakthroughs of HIV-related fatigue...
Low-level HIV viremia: Definitions, predictors, mechanisms, and clinical outcomes
Key take-home messages The definitions of optimal viral suppression, low-level viremia, blips, virologic failure, and recommended management approaches to low-level viremia vary greatly across studies and clinical guidelines. There is...
