Category Archives: Treatment

Network meta-analysis of post-exposure prophylaxis randomized clinical trials

2020

OBJECTIVES: We performed a network meta-analysis of PEP randomized clinical trials to evaluate the best regimen. METHODS: After MEDLINE/Pubmed search, studies were included if: (1) were randomized, (2) comparing at...

Exercise and antiretroviral adherence in adults living with HIV: A systematic review

2020

This systematic review assessed the relationship between exercise and ART adherence in adults living with HIV. A comprehensive search through June 2020 for relevant studies was conducted, and PRISMA guidelines...

Factors Related to Hair Antiretroviral Concentration: A Systematic Review of Global Literature

2019

Assessment of antiretroviral (ARV) concentration in hair (hair antiretroviral concentration [HAC]) is one of the latest non-invasive innovations for measuring long-term ARV adherence. We performed a systematic review following Preferred...

Aging with HIV

2019

PURPOSE OF REVIEW: This review points out unmet medical needs and open research questions of older adults living with HIV. Starting from the definition of aging in HIV, it explores...

The pharmacogenetics of efavirenz metabolism in children: The potential genetic and medical contributions to child development in the context of long-term ARV treatment

2020

Efavirenz (EFV) is a well-known, effective anti-retroviral drug long used in first-line treatment for children and adults with HIV and HIV/AIDS. Due to its narrow window of effective concentrations, between...

Interventions to improve medication adherence in adolescents with HIV: A systematic review and meta-analysis

2020

As of 2017, 1.8 million people living with HIV (PLWH) were adolescents between ages 10 and 19, accounting for 5% of all PLWH and 590,000 people between the ages 15...

Adolescent mothers affected by HIV and their children: A scoping review of evidence and experiences from sub-Saharan Africa

2020

While adolescents have received increasing attention in the global HIV response and international strategies and commitments, adolescent mothers and their children remain largely overlooked in research, funding and, programming for...

Home-based care, the missing link in caring of patients living with HIV/AIDS and their family members: A narrative review

2020

Inconsistencies between the number of patients, qualified caregivers and lack of adequate services and resources in the healthcare systems for people living with HIV/AIDS have led to the idea of...

Antiretroviral therapy improves neurocognitive impairment in people living with HIV? A meta-analysis

2020

Objectives: Although effective antiretroviral therapy (ART) has been used for more than two decades, HIV-associated neurocognitive disorder remains prevalent. Thus, whether ART can improve neurocognitive impairment is controversial. This review...

impact of pre-antiretroviral therapy CD4 counts on drug resistance and treatment failure: A systematic review

2020

The continuous rising of HIV drug resistance in low- and middle-income countries and its impact on treatment failure is a growing threat for the HIV treatment response. This review aimed...

Barriers to older adults seeking sexual health advice and treatment: A scoping review

2020

BACKGROUND: Sexual health is an integral part of overall health in older age. Research consistently reports that heterosexual and queer older people tend not to disclose sexual concerns and difficulties...

Impact of mobile phone-based interventions on methamphetamine use and high-risk sexual behaviors in men who have sex with men (MSM): A systematic review

2020

Background: Today, increased use of methamphetamine in homosexual men is associated with high-risk sexual behaviors and (HIV) epidemic. Mobile phone-based interventions are an accessible and rapid method to provide healthcare...

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