Category Archives: Treatment
Changing knowledge and attitudes towards HIV Treatment-as-Prevention and “Undetectable=Untransmittable”: A systematic review
People on HIV treatment with undetectable virus cannot transmit HIV sexually (Undetectable=Untransmittable, U=U). However, the science of treatment-as-prevention (TasP) may not be widely understood by people with and without HIV...
Effect of community-based interventions targeting female sex workers along the HIV care cascade in sub-Saharan Africa: A systematic review and meta-analysis
BACKGROUND: Female sex workers are extremely vulnerable and highly susceptible to being infected with human immunodeficiency virus. As a result, community-based targeted interventions have been recommended as one of the...
A systematic review of the effectiveness of non-health facility based care delivery of antiretroviral therapy for people living with HIV in sub-Saharan Africa measured by viral suppression, mortality and retention on ART
BACKGROUND: Alternative models for sustainable antiretroviral treatment (ART) delivery are necessary to meet the increasing demand to maintain population-wide ART for all people living with HIV (PLHIV) in sub-Saharan Africa....
mHealth interventions for treatment adherence and outcomes of care for cardiometabolic disease among adults living with HIV: Systematic review
BACKGROUND: The success of antiretroviral therapy has led to an increase in life expectancy and an associated rise in the risk of cardiometabolic diseases (CMDs) among people living with HIV....
Prevalence and factors associated with common mental disorders in young people living with HIV in sub-Saharan Africa: A systematic review
INTRODUCTION: Common mental disorders (CMDs) particularly depression and anxiety, are highly comorbid with HIV also in young people living with HIV (YLWH). In sub-Saharan Africa (SSA) where most YLWH reside,...
Cerebrospinal fluid immune markers and HIV-associated neurocognitive impairments: A systematic review
HIV-1 is responsible for the development of a spectrum of cognitive impairments known as HIV-associated neurocognitive disorder (HAND). In the era of antiretroviral therapy (ART), HAND remains prevalent in people...
Association of HIV infection and antiretroviral therapy With arterial stiffness: A systematic review and meta-analysis
Incidence of cardiovascular disease in people living with HIV has increased as overall survival has improved because of combination antiretroviral therapy (cART). Arterial stiffness is a composite indicator of cardiovascular...
Causally interpretable meta-analysis: Application in adolescent HIV prevention
Endowing meta-analytic results with a causal interpretation is challenging when there are differences in the distribution of effect modifiers among the populations underlying the included trials and the target population...
