Category Archives: Treatment

Comparative efficacy and safety and dolutegravir and lamivudine in treatment naive HIV patients

2019

Objective: Compare the efficacy and safety of the 2-drug antiretroviral therapy regimen dolutegravir + lamivudine (DTG + 3TC) with traditional 3-drug regimens in treatment-naive patients with HIV-1. Design: Data from double-blind, randomized...

Tenofovir-associated kidney disease in Africans: A systematic review

2019

BACKGROUND: Data on chronic kidney disease development in HIV infection is important towards building a comprehensive knowledge of HIV, ageing and polypharmacy in Africa. Several previous studies on tenofovir-associated kidney...

Recent interventions to improve retention in HIV care and adherence to antiretroviral treatment among adolescents and youth: A systematic review

2019

Adolescents represent a growing proportion of people living with HIV worldwide and the highest risk population group for treatment attrition and AIDS-related mortality. There is an urgent need to design,...

Patho-immune mechanisms of hypertension in HIV: A systematic and thematic review

2019

PURPOSE OF REVIEW: To systematically review recent findings on the role of immune cell activation in the pathogenesis of hypertension in people living with HIV (PLWH) and compare studies from...

Do quality improvement initiatives improve outcomes for patients in antiretroviral programs in low- and middle-income countries? A systematic review

2019

Background: There have been a range of quality improvement (QI) and quality assurance initiatives in low- and middle-income countries to improve antiretroviral therapy (ART) treatment outcomes for people living with HIV....

Ghana’s HIV epidemic and PEPFAR’s contribution towards epidemic control

2019

Background: The aim of this review was to summarize the data on HIV/AIDS epidemiology and affected populations in Ghana and to describe the United States President’s Emergency Plan for Emergency...

Effects of malaria/helminthic coinfections on cervical cancer progression among sub Saharan African women on highly active antiretroviral therapy: A scoping review

2019

In Africa, the HIV prevalence in rural areas has begun to reach levels estimated within urban settings, where women are also more at risk for both malaria and intestinal parasitic...

Integration of HIV testing services into family planning services: A systematic review

2019

BACKGROUND: Despite significant interest in integrating sexual and reproductive health (SRH) services into HIV services, less attention has been paid to linkages in the other direction. Where women and girls...

Integration of care for HIV and opioid use disorder

2019

OBJECTIVE: We sought to identify optimal strategies for integrating HIV- and opioid use disorder-(OUD) screening and treatment in diverse settings. DESIGN: Systematic review. METHODS: We searched Ovid MEDLINE, PubMed, Embase,...

Antiretroviral concentration in hair as a measure for antiretroviral medication adherence: A systematic review of global literature

2019

This review aims to validate hair antiretroviral concentration (HAC) as a measure for antiretroviral medication adherence. This review included 31 studies that analyzed a total of 11 ARV drugs in...

Long-term effects of psychological interventions to improve adherence to antiretroviral treatment in HIV-infected persons: A systematic review and meta-analysis

2019

We examined the efficacy of psychological adherence-enhancing interventions (AEIs) compared with usual care in HIV-infected adults under antiretroviral treatment (ART) by focusing on adherence and clinical HIV markers as outcomes...

Challenges and support for quality of life of youths living with HIV/AIDS in schools and larger community in East Africa: A systematic review

2019

BACKGROUND: Youths living with HIV/AIDS (YLWHA) experience innumerable challenges within schools and the larger community. Nonetheless, these environments are potential sources of support for such youths. This review provides a...

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