Category Archives: Treatment
Associations between anxiety and adherence to antiretroviral medications in low- and middle-income countries: A systematic review and meta-analysis
Untreated mental health disorders among people living with HIV (PLHIV) may prevent low- and middle-income countries (LMICs) from achieving the UNAIDS 90-90-90 targets. Anxiety disorders may be associated with decreased...
Older African Americans and the HIV care continuum: A systematic review of the literature, 2003-2018
Evidence suggests that racial disparities in the HIV care continuum persist in older age groups, particularly among African Americans. The objective of this systematic review was to identify factors that...
HIV, depression, and cognitive impairment in the era of effective antiretroviral therapy
PURPOSE OF REVIEW: Mental health disorders, especially depression, are prevalent among people living with HIV (PLWH) and are associated with cognitive impairment (CI) among HIV-uninfected (HIV-) individuals. We conducted a...
Comparison of the predictive performance of adherence measures for virologic failure detection in people living with HIV: A systematic review and pairwise meta-analysis
A critical feature of an adherence assessment tool is its ability to predict virologic failure in people living with HIV (PLHIV). We, therefore, aimed to compare the predictive performance of...
Effectiveness of ombitasvir/paritaprevir/ritonavir, dasabuvir for HCV in HIV/HCV coinfected subjects: A comprehensive analysis
BACKGROUND: Data on the treatment of patients with hepatitis C virus (HCV)/human immunodeficiency virus (HIV) coinfection remains limited. A comprehensive analysis was performed to evaluate the efficacy and safety of...
Content guidance for mobile phones short message service (SMS)-based antiretroviral therapy adherence and appointment reminders: A review of the literature
Mobile phones are increasingly being used to support health activities, including the care and management of people living with HIV/AIDS. Short message service (SMS) has been explored as a means...
Epidemiology of depressive disorders in people living with HIV in Africa: A systematic review and meta-analysis: Burden of depression in HIV in Africa
OBJECTIVE: The burden of HIV infection is higher in Africa where 70% of people living with HIV (PLHIV) resides. Since depression can negatively impact the course of HIV infection, it...
Unintended pregnancy in women living with HIV in sub-Saharan Africa: A systematic review and meta-analysis
In 2014, about 1.5 million pregnancies occurred among HIV-positive women in low and middle-income countries. To pool magnitude and factors associated with unintended pregnancy in women living with HIV in...
Global research output on HIV/AIDS-related medication adherence from 1980 to 2017
BACKGROUND: Human Immunodeficiency Virus (HIV) and Acquired Immunodeficiency Syndrome (AIDS) are global health burden. Medication adherence in people living with HIV (PLWH) is a key element in reducing morbidity and...
Sensitivity and specificity of WHO’s recommended four-symptom screening rule for tuberculosis in people living with HIV: A systematic review and meta-analysis
BACKGROUND: Since 2011, WHO recommends a four-symptom screening rule to exclude active tuberculosis in people living with HIV before starting tuberculosis preventive treatment (ie, absence of current cough, weight loss,...