Category Archives: Treatment

Loss to follow-up from antiretroviral therapy clinics: A systematic review and meta-analysis of published studies in South Africa from 2011 to 2015

2019

Background: South Africa has the largest antiretroviral therapy (ART) programme in the world. To optimise programme outcomes, it is critical that patients are retained in care and that retention is...

Analysis of systematic reviews of medication adherence interventions for persons with HIV, 1996–2017

2019

This overview of reviews summarizes the evidence from systematic reviews (SR) on the effectiveness of antiretroviral therapy (ART) adherence interventions for people with HIV (PWH) and descriptively compares adherence interventions...

Using discrete choice experiments to develop and deliver patient-centered psychological interventions: A systematic review

2020

Developing and/or tailoring psychological interventions to align with patient preferences is a critical component of patient-centered care and has the potential to improve patient engagement and treatment outcomes. Discrete choice...

HBV infection in HIV-driven immune suppression

2019

Worldwide, approximately 10% of all human immunodeficiency virus (HIV)-infected people are also chronically coinfected with hepatitis B virus (HBV). HBV infection has a poor prognosis in HIV-positive people and has...

HIV-1, HAART and cancer: A complex relationship

2019

HIV infected people are at higher risk of developing cancer, although it is globally diminished in the era of highly active antiretroviral treatment (HAART). Recently, antioncogenic properties of some HAART...

Disclosure of HIV status to children in sub-Saharan Africa: A systematic review

2019

Background and objectives: This study aimed to assess the level of HIV disclosure to children in sub-Saharan Africa as it relates to prevalence of disclosure, barriers, merits and demerits, timing...

Peer-led self-management Interventions and adherence to antiretroviral therapy among people living with HIV: A systematic review

2019

Adherence to antiretroviral therapy (ART) is essential to reduce morbidity and mortality among people living with HIV (PLWH). However, adherence remains suboptimal, and PLWH may benefit from more self-management support...

Barriers and facilitators to the successful transition of adolescents living with HIV from pediatric to adult care in low and middle-income countries: A systematic review and policy analysis

2019

The purpose of this systematic review was twofold. First, we sought to summarize the literature on barriers and facilitators to successful healthcare transition for adolescents living with HIV from low-...

Barriers to the use of mobile health in improving health outcomes in developing countries: Systematic review

2019

BACKGROUND: The use of mobile health (mHealth) technologies to improve population-level health outcomes around the world has surged in the last decade. Research supports the use of mHealth apps to...

Interventions to reduce gender-based violence among young people living with or affected by HIV/AIDS in low-income and middle-income countries

2019

OBJECTIVE(S): This study explored the effectiveness of gender-based violence (GBV) interventions on young people living with or affected by HIV in low- and middle-income countries (LMICs). DESIGN: Systematic review and...

Definition of immunological non-response to antiretroviral therapy: A systematic review

2019

BACKGROUND: Terms and criteria to classify people living with HIV on antiretroviral therapy (ART) who fail to achieve satisfactory CD4 T cell counts are heterogeneous, and need revision and summarization....

Getting youth PrEPared: Adolescent consent laws and implications for the availability of PrEP among youth in countries outside of the United States

2019

INTRODUCTION: Youth under the age of 25 are at high risk for HIV infection. While pre-exposure prophylaxis (PrEP) has the potential to curb new infections within this population, it is...

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