Category Archives: Treatment

Challenges facing HIV treatment as prevention in Brazil: An analysis drawing on literature on testing

2019

According to current global AIDS guidelines, HIV testing is key to the success of the ‘treatment as prevention’ (TasP) strategy and the control of AIDS. In view of Brazil’s commitment...

Impact of community pharmacist-led interventions in chronic disease management on clinical, utilization, and economic outcomes: An umbrella review

2019

BACKGROUND: Chronic disease represents a significant burden to the United States (US) health care system, with approximately 50% of all adults in the US having one or more chronic disease...

Cost of differentiated HIV antiretroviral therapy delivery strategies in sub-Saharan Africa: A systematic review

2019

BACKGROUND: Efficient and scalable models for HIV treatment are needed to maximize health outcomes with available resources. By adapting services to client needs, differentiated antiretroviral therapy (DART) has the potential...

ART adherence clubs in the Western Cape of South Africa: What does the sustainability framework tell us? A scoping literature review

2019

INTRODUCTION: In 2007, the antiretroviral therapy (ART) adherence club (AC) model was introduced to South Africa to combat some of the health system barriers to ART delivery, such as staff...

Taiwan guideline on oral pre-exposure prophylaxis for HIV prevention – 2018 update

2019

Pre-exposure prophylaxis (PrEP) for prevention of human immunodeficiency virus infection is proved to be effective and has been implemented worldwide. This article introduces the guideline development and revised recommendations and...

Meta-analysis and systematic review of the efficacy and resistance for human immunodeficiency virus type 1 integrase strand transfer inhibitors

2019

Integrase strand transfer inhibitors (INSTIs) are the most recent class of antiretroviral drugs with potent and durable antiviral activity used to treat human immunodeficiency virus type 1 (HIV-1) infection. However,...

What do HIV-positive drug users’ experience tell us about their antiretroviral medications taking? An international integrated literature review

2019

BACKGROUND AND AIMS: HIV-positive drug users’ poor adherence to antiretroviral regimens can pose a significant and negative impact on individual and global health. This review aims to identify knowledge gaps...

Necessity and concerns beliefs and HIV medication adherence: A systematic review

2019

According to the Necessity-Concerns Framework, beliefs about medication necessity and concerns are two core themes from diverse patient medication beliefs across chronic illnesses that may directly influence adherence. Past work...

Electronic health interventions to improve adherence to antiretroviral therapy in people living With HIV: Systematic review and meta-analysis

2019

BACKGROUND: Electronic health (eHealth) is increasingly used for self-management and service delivery of HIV-related diseases. With the publication of studies increasingly focusing on antiretroviral therapy (ART) adherence, this makes it...

Clinical review report: Doravirine (Pifeltro)

2019

The objective of this systematic review was to evaluate the beneficial and harmful effects of doravirine, in combination with other antiretroviral medicinal products, for the treatment of HIV-1 infection in...

HIV-1, HAART and cancer: A complex relationship

2019

HIV infected people are at higher risk of developing cancer, although it is globally diminished in the era of highly active antiretroviral treatment (HAART). Recently, antioncogenic properties of some HAART...

Disclosure of HIV status to children in sub-Saharan Africa: A systematic review

2019

Background and objectives: This study aimed to assess the level of HIV disclosure to children in sub-Saharan Africa as it relates to prevalence of disclosure, barriers, merits and demerits, timing...

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