Category Archives: Treatment

Nutrition and HIV

2018

Key take-home messages Nutrition is an important component of care for people living with HIV. Nutritional needs for people living with HIV can vary; therefore, dietary recommendations should be individualized...

Does per-act HIV-1 transmission risk through anal sex vary by gender? An updated systematic review and meta-analysis

2018

Quantifying HIV-1 transmission risk per-act of anal intercourse (AI) is important for HIV-1 prevention. We updated previous reviews by searching Medline and Embase to 02/2018. We derived pooled estimates of...

HIV services in rural and remote communities

2013

Key take-home messages People with or at risk of HIV who live in rural communities face complex challenges accessing services, including stigma, lack of services, transportation issues and some population-specific...

Considerations for the clinical management of HIV elite controllers

2018

Key take-home messages Fewer than one percent of people living with HIV are “elite controllers” (i.e. people who can spontaneously control HIV viral load without antiretroviral therapy). The ability of...

Assessing the efficacy of lopinavir/ritonavir-based preferred and alternative second-line regimens in HIV-infected patients: A meta-analysis of key evidence to support WHO recommendations

2018

Background: Nucleoside reverse transcriptase inhibitors (NRTIs) and non-NRTIs (NNRTIs) with boosted protease inhibitors are included in standardized first-line and second-line regimens. Recent World Health Organization (WHO) guidelines recommend a boosted...

Gay men’s attitudes towards and perceptions of viral load and treatment as prevention

2014

Key take-home messages Findings from recent studies have highlighted the potential for antiretroviral therapy to prevent HIV by reducing an HIV-positive person’s viral load. Prevention experts are concerned that active...

Sports and social gay networks for HIV prevention

2010

Key take-home messages We were unable to locate any research evidence assessing sport and/or social gay networks as HIV prevention strategies. The studies we did identify assess social networks as...

Implementation of eHealth interventions across the HIV care cascade: A review of recent research

2018

PURPOSE OF REVIEW: We review recent implementation science focusing on eHealth interventions to improve outcomes along the HIV care cascade. We highlight several gaps in the eHealth implementation literature and...

Peer-based programs to support antiretroviral adherence

2014

Key take-home messages There is some evidence to suggest that peer-based interventions can be effective and cost-effective tools for improving adherence to HAART among people living with HIV. However, in...

A meta-analysis comparing 48-week treatment outcomes of single and multi-tablet antiretroviral regimens for the treatment of people living with HIV

2018

OBJECTIVES: To compare outcomes with single tablet regimens (STR) versus multi-tablet regimens (MTR) for human immunodeficiency virus (HIV) treatment using published data. DESIGN: Systematic review and random-effects meta-analysis of literature...

Effectiveness of macronutrient supplementation on nutritional status and HIV/AIDS progression: A systematic review and meta-analysis

2018

BACKGROUND & AIMS: Malnutrition is common in Sub-Saharan Africa, weakening the immune function of persons living with HIV infection (PLWH). Being malnourished at the initiation of antiretroviral therapy (ART) leads...

HIV medication and depression

2009

Key take-home messages The Ontario HIV and Substance Use Training Program offers workshops across Ontario for counselors working in the field. In the past these workshops have advised counselors to...

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