Category Archives: Treatment

Considerations for the clinical management of HIV elite controllers

2018

Key take-home messages Fewer than one percent of people living with HIV are “elite controllers” (i.e. people who can spontaneously control HIV viral load without antiretroviral therapy). The ability of...

Assessing the efficacy of lopinavir/ritonavir-based preferred and alternative second-line regimens in HIV-infected patients: A meta-analysis of key evidence to support WHO recommendations

2018

Background: Nucleoside reverse transcriptase inhibitors (NRTIs) and non-NRTIs (NNRTIs) with boosted protease inhibitors are included in standardized first-line and second-line regimens. Recent World Health Organization (WHO) guidelines recommend a boosted...

Gay men’s attitudes towards and perceptions of viral load and treatment as prevention

2014

Key take-home messages Findings from recent studies have highlighted the potential for antiretroviral therapy to prevent HIV by reducing an HIV-positive person’s viral load. Prevention experts are concerned that active...

Sports and social gay networks for HIV prevention

2010

Key take-home messages We were unable to locate any research evidence assessing sport and/or social gay networks as HIV prevention strategies. The studies we did identify assess social networks as...

Implementation of eHealth interventions across the HIV care cascade: A review of recent research

2018

PURPOSE OF REVIEW: We review recent implementation science focusing on eHealth interventions to improve outcomes along the HIV care cascade. We highlight several gaps in the eHealth implementation literature and...

Peer-based programs to support antiretroviral adherence

2014

Key take-home messages There is some evidence to suggest that peer-based interventions can be effective and cost-effective tools for improving adherence to HAART among people living with HIV. However, in...

A meta-analysis comparing 48-week treatment outcomes of single and multi-tablet antiretroviral regimens for the treatment of people living with HIV

2018

OBJECTIVES: To compare outcomes with single tablet regimens (STR) versus multi-tablet regimens (MTR) for human immunodeficiency virus (HIV) treatment using published data. DESIGN: Systematic review and random-effects meta-analysis of literature...

Effectiveness of macronutrient supplementation on nutritional status and HIV/AIDS progression: A systematic review and meta-analysis

2018

BACKGROUND & AIMS: Malnutrition is common in Sub-Saharan Africa, weakening the immune function of persons living with HIV infection (PLWH). Being malnourished at the initiation of antiretroviral therapy (ART) leads...

HIV medication and depression

2009

Key take-home messages The Ontario HIV and Substance Use Training Program offers workshops across Ontario for counselors working in the field. In the past these workshops have advised counselors to...

Motivational interviewing

2014

Key tale-home messages Interventions that make use of motivational interviewing can be effective in changing risk behaviours for people living with HIV; the longer the motivational interviewing intervention, the more...

Interventions for developmental delays in children born to HIV-infected mothers: A systematic review

2018

Children born to HIV-infected mothers have worse developmental outcomes compared to HIV-unexposed children. However, little is known about interventions to improve developmental outcomes in this population. This study systematically reviews...

Self-management of HIV and diabetes in African American women: A systematic review of qualitative literature

2018

Purpose The purpose of this systematic review of qualitative literature was (1) to identify self-management strategies, (2) to identify women’s barriers to self-management, and (3) to compare self-management strategies of...

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