Category Archives: Treatment
Sensitivity and specificity of WHO’s recommended four-symptom screening rule for tuberculosis in people living with HIV: A systematic review and meta-analysis
BACKGROUND: Since 2011, WHO recommends a four-symptom screening rule to exclude active tuberculosis in people living with HIV before starting tuberculosis preventive treatment (ie, absence of current cough, weight loss,...
Self-stigma reduction interventions for people living with HIV/AIDS and their families: A systematic review
Stigma is a primary concern for people living with human immunodeficiency virus (HIV)/AIDS (PLWHA), and has great impact on their and their family members’ health. While previous reviews have largely...
Psychosocial factors associated with persistent pain in people with HIV: A systematic review with meta-analysis
Chronic pain remains a prevalent and disabling problem for people living with the human immunodeficiency virus (HIV) in the current antiretroviral (ART) treatment era. Psychosocial treatments may have promise for...
Coordination and delivery of HIV prevention, treatment, care and support by nurse practitioners
Key take-home messages • Medical care, including primary care, delivered by nurse practitionersis often equivalent to the care administered by physicians. Caredelivered by nurse practitioners generally rates higher on measures...
Women, incarceration and HIV: A systematic review of HIV treatment access, continuity of care and health outcomes across incarceration trajectories
OBJECTIVE: To systematically review the literature on gendered implications of incarceration for HIV outcomes and engagement in care for women living with HIV (WLWH). DESIGN: We systematically searched 7 bibliographic...
The Impact of co-morbid severe mental illness and HIV upon mental and physical health and social outcomes: A systematic review
Our aim was to review the evidence related to the impact of co-morbid severe mental illness SMI (schizophrenia, schizoaffective and bipolar disorder) and HIV upon mental health, physical health and...
HIV-associated cardiovascular disease: Importance of platelet activation and cardiac fibrosis in the setting of specific antiretroviral therapies
HIV infection is a risk factor for cardiovascular disease (CVD). This risk is accentuated by certain combination antiretroviral therapies (cARTs), independent of their effects on lipid metabolism and insulin sensitivity....
Comparative safety and effectiveness of perinatal antiretroviral therapies for HIV-infected women and their children: Systematic review and network meta-analysis including different study designs
BACKGROUND: Nearly all newly infected children acquire Human Immunodeficiency virus (HIV) via mother-to-child transmission (MTCT) during pregnancy, labour or breastfeeding from untreated HIV-positive mothers. Antiretroviral therapy (ART) is the standard...
Evaluation of blood-based antibody rapid testing for HIV early therapy: A meta-analysis of the evidence
Background: Western blot (WB) assay is considered the gold standard test for HIV infection confirmation. However, it requires technical expertise and is quite time-consuming. WHO recommends blood-based rapid diagnosis to...
