Category Archives: Treatment

Individual patient data meta-analysis of randomized controlled trials of dual therapy with a boosted PI plus lamivudine for maintenance of virological suppression: GeSIDA study 9717

2018

Background: Dual therapy (DT) with a ritonavir-boosted PI (PI/r) plus lamivudine has proven non-inferior (12% margin) to triple therapy (TT) with PI/r plus two nucleos(t)ide reverse transcriptase inhibitors [N(t)RTIs] in...

Sexual abstinence among people living with HIV/AIDS

2011

Key take-home messages Diagnosis of HIV infection can have far-reaching implications: people’s sexual interest, the pleasure they derive from sex, their sense of attractiveness or appeal as a sexual partner...

Impact of successful hepatitis C treatment on quality of life

2016

Key take-home messages People living with HCV who receive treatment and achieve sustained virologic response (SVR) have better healthrelated quality of life scores than people who do not respond to...

Breast cancer and HIV in Sub-Saharan Africa: A complex relationship

2017

INTRODUCTION: The number and lifespan of individuals living with HIV have increased significantly with the scale-up of antiretroviral therapy. Furthermore, the incidence of breast cancer in women with HIV is...

Behavioral and cognitive interventions to improve treatment adherence and access to HIV care among older adults in sub-Saharan Africa: An updated systematic review

2018

BACKGROUND: Approximately 14% of Africans infected with HIV are over the age of 50, yet few intervention studies focus on improving access to care, retention in care, and adherence to...

East and South East Asian women’s sexual health

2012

Key take-home messages There is very little research that exclusively focuses on the sexual health and prevention of sexually transmitted infections (STIs) and/or HIV prevention for East and South East...

The effect of mental health issues on sexual risk behaviours and antiretroviral medication adherence among men who have sex with men

2016

Key take-home messages Men who have sex with men and other sexual minorities may experience mental health problems that are rooted in sexual minority stress. Multiple mental health problems can...

Effectiveness of short message services and voice call interventions for antiretroviral therapy adherence and other outcomes: A systematic review and meta-analysis

2018

BACKGROUND: The potential of using mobile phone technologies to improve antiretroviral therapy (ART) adherence has provided a new facet to human immunodeficiency virus (HIV) research. The quality of evidence and...

Is alcohol use associated with increased risk of developing adverse health outcomes among adults living with human immunodeficiency virus: A systematic review

2018

BACKGROUND: Alcohol use is associated with many HIV-related behaviors that are associated with increased risk of reinfection, transmission, and poorer health outcomes in people living with HIV (PLHIV). The population...

A meta-analysis of effectiveness of interventions to improve adherence in pregnant women receiving antiretroviral therapy in sub-Saharan Africa

2018

OBJECTIVE: We evaluated the effectiveness of interventions aimed at improving antiretroviral therapy (ART) adherence during pregnancy in sub-Saharan Africa. METHODS: For this meta-analysis, the following databases were searched: MEDLINE Complete,...

Use of antiretroviral therapy during pregnancy and adverse birth outcomes among women living with HIV-1 in low- and middle-income countries: A systematic review

2018

BACKGROUND: Worldwide, nearly 18 million women of reproductive age are living with HIV-1. Although increased access to antiretroviral therapy (ART) during pregnancy has significantly reduced HIV-1 mother-to-child transmission (MTCT), a...

Comparison of antiretroviral therapy adherence among HIV-infected older adults with younger adults in Africa: Systematic review and meta-analysis

2018

As access to antiretroviral treatment in low- and middle-income countries improves, the number of older adults (aged >/= 50 years) living with HIV is increasing. This study compares the adherence...

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