Category Archives: Treatment
The relationship between stress and clinical outcomes for persons living with HIV/AIDS: A systematic review of the global literature
For persons living with HIV/AIDS, the relationship between stress and clinical outcomes has received little attention in current research, yet represents an important area for future research and intervention. Chronic...
Nanotechnology and the future of condoms in the prevention of sexually transmitted infections
Objective: The human immunodeficiency virus (HIV) is among the utmost destructive viruses humankind has ever faced in almost four decades. It carries with it profound socioeconomic and public health implications....
State-level spending on health care and social services for people living with HIV/AIDS in the USA: A systematic review
Every year for the past decade, approximately 50,000 people have been diagnosed with HIV or AIDS in the USA, and the incidence of HIV/AIDS varies considerably from state to state....
Community health worker interventions to promote psychosocial outcomes among people living with HIV — A systematic review
BACKGROUND: Community health worker (CHW) interventions are a successful strategy to promote health among HIV-negative and persons living with HIV (PLWH). Psychosocial factors are critical dimensions of HIV/AIDS care contributing...
CD4 cell count threshold for cryptococcal antigen screening of HIV-infected individuals: A systematic review and meta-analysis
Background: Current guidelines recommend screening all people living with human immunodeficiency virus (PLHIV) who have a CD4 count ≤100 cells/µL for cryptococcal antigen (CrAg) to identify those patients who could benefit...
Prevalence and associated factors of depression among PLHIV in Ethiopia: Systematic review and meta-analysis, 2017
Background: Depression is a substantial contributor to the global burden of disease and affects people in all communities across the globe. Depression is the most common psychiatric problem associated with...
Factors impacting antiretroviral therapy adherence among human immunodeficiency virus-positive adolescents in Sub-Saharan Africa: A systematic review
OBJECTIVES: Eighty-two percent of human immunodeficiency virus (HIV)-positive adolescents live in Sub-Saharan Africa (SSA). Despite the availability of antiretroviral therapy (ART), adherence levels are suboptimal, leading to poor outcomes. This...
Influence of AIDS antiretroviral therapy on the growth pattern
OBJECTIVES: Human immunodeficiency virus infection can result in the early impairment of anthropometric indicators in children and adolescents. However, combined antiretroviral therapy has improved, in addition to the immune response...
From CD4-based initiation to treating all HIV-infected adults immediately: An evidence-based meta-analysis
Background: The World Health Organization (WHO) Consolidated antiretroviral therapy (ART) guidelines set the CD4(+) T-cell counts threshold to 500 cells/mm(3) in 2013, and 2015 guidelines recommend treating all HIV-infected adults...
Linking private, for-profit providers to public sector services for HIV and tuberculosis co-infected patients: A systematic review
BACKGROUND: Tuberculosis (TB) is the leading cause of infectious disease deaths worldwide and is the leading cause of death among people with HIV. The World Health Organization (WHO) has called...
Review of differentiated approaches to antiretroviral therapy distribution
In response to global trends of maximizing the number of patients receiving antiretroviral therapy (ART), this review summarizes literature describing differentiated models of ART distribution at facility and community levels...
Doing patient-centredness versus achieving public health targets: A critical review of interactional dilemmas in ART adherence support
Anti-retroviral Therapy (ART) transformed HIV into a chronic disease but its individual and public health benefits depend on high levels of adherence. The large and rising number of people on...
