Category Archives: Engagement and Care Cascade
Evidence gaps on weight gain in people living with HIV: A scoping review to define a research agenda
BACKGROUND: Combined antiretroviral therapy (cART) dramatically improved survival in people living with HIV (PLWH) but is associated with weight gain (WG), raising concern for a possible obesity epidemic in PLWH....
The innovative use of qualitative and mixed methods research to advance improvements along the HIV prevention and care continua
PURPOSE OF REVIEW: Despite enormous advances in prevention and care modalities, HIV continues to burden populations around the globe and is largely driven by social and behavioral processes. Mixed methods...
The effect of antiretroviral therapy on the periodontal conditions of patients with HIV infection: A systematic review and meta-analysis
Aim: To assess any differences (1) in the prevalence of periodontitis and necrotizing periodontal diseases, specifically necrotizing gingivitis (NG) and necrotizing periodontitis (NP) between HIV patients receiving antiretroviral therapy (HAART) and...
A scoping review of methods used to assess medication adherence in patients with chronic conditions
BACKGROUND: Medication nonadherence of patients with chronic conditions is a complex phenomenon contributing to increased economic burden and decreased quality of life. Intervention development relies on accurately assessing adherence but...
Low-level viraemia: An emerging concern among people living with HIV in Uganda and across sub-Saharan Africa
Attaining viral load (VL) suppression for over 95% of the people living with HIV on antiretroviral therapy is a fundamental step in enabling Uganda and other sub-Saharan African countries to...
Effect of social support interventions on adherence to antiretroviral therapy among people living with HIV: A systematic review and meta-analysis
This systematic review and meta-analysis examined the effects of social support interventions (SSIs) on adherence to antiretroviral therapy (ART) among people living with HIV. We systematically searched Web of Science,...
First line antiretroviral treatment failure and its association with drug substitution and sex among children in Ethiopia: Systematic review and meta-analysis
Antiretroviral Treatment (ART) has significantly decreased HIV-related morbidity and mortality among children despite the issue of drug resistance and subsequent treatment failure appearing as a challenge. Different studies have been...
Effectiveness and safety of statins on outcomes in patients with HIV infection: A systematic review and meta-analysis
Statins are hypolipidaemic in human immunodeficiency virus (HIV) positive individuals. However, their effect on all-cause mortality and rate of discontinuation is unclear. We conducted a systematic review to evaluate the...
Antiretroviral drugs for treatment and prevention of HIV infection in adults: 2022 Recommendations of the International Antiviral Society-USA Panel
IMPORTANCE: Recent advances in treatment and prevention of HIV warrant updated recommendations to guide optimal practice. OBJECTIVE: Based on a critical evaluation of new data, to provide clinicians with recommendations...
Barriers and facilitators to the implementation and scale up of differentiated service delivery models for HIV treatment in Africa: A scoping review
BACKGROUND: In the face of health-system constraints, local policymakers and decision-makers face difficult choices about how to implement, expand and institutionalize antiretroviral therapy (ART) services. This scoping review aimed to...
