Category Archives: Prevention, Engagement and Care Cascade
The effect of probiotics, prebiotics, and synbiotics on cd4 counts in HIV-infected patients: A systematic review and meta-analysis
BACKGROUND: Probiotics as a potential adjuvant therapy may improve the restoration of the intestinal CD4(+) T-cell population in HIV-infected patients, whereas findings from clinical trials are inconsistent. This systematic review...
Approaches to transitioning women into and out of prevention of mother-to-child transmission of HIV services for continued ART: A systematic review
Introduction: Women living with HIV are required to transition into the prevention of mother-to-child transmission of HIV (PMTCT) services when they become pregnant and back to ART services after delivery....
Prevalence of pretreatment HIV drug resistance in key populations: A systematic review and meta-analysis
Introduction: WHO’s 2019 report on HIV drug resistance (HIVDR) documents a high prevalence of pretreatment drug resistance (PDR) among populations initiating first-line antiretroviral therapy (ART) in low- and middle-income countries...
The HIV prevalence in older men who have sex with men in Western & Central Europe and North America-A meta-analysis
The age of patients living with human immunodeficiency virus (HIV) is increasing and the greatest proportion of aged HIV patients occurred in Western and Central Europe and North America (WCENA)....
A review of cultural influences on risk for HIV and culturally-responsive risk mitigation strategies among African immigrants in the US
There is a paucity of research on HIV risk factors and risk reduction among African immigrants living in the US. This is despite the fact that the literature on HIV...
Theories of change for e-health interventions targeting HIV/STIs and sexual risk, substance use and mental ill health amongst men who have sex with men: Systematic review and synthesis
BACKGROUND: Sexual risk, substance use, and mental ill health constitute a syndemic of co-occurring, mutually reinforcing epidemics amongst men who have sex with men (MSM). Developed since 1995, e-health interventions...
Potential challenges to sustained viral load suppression in the HIV treatment programme in South Africa: A narrative overview
BACKGROUND: South Africa, with one of the highest HIV prevalences in the world, introduced the universal test and treat (UTT) programme in September 2016. Barriers to sustained viral suppression may...
Depressive symptoms and their determinants in patients who are on antiretroviral therapy in the case of a low-income country, Ethiopia: A systematic review and meta-analysis
Background: The presence of depression in people living with HIV/AIDS could lead to non-adherence to antiretroviral medications. It also leads to further comorbid and opportunistic illness and then lowering the...
Mapping evidence of mobile health technologies for disease diagnosis and treatment support by health workers in sub-Saharan Africa: A scoping review
BACKGROUND: The rapid growth of mobile technology has given rise to the development of mobile health (mHealth) applications aimed at treating and preventing a wide range of health conditions. However,...
Atazanavir / ritonavir versus Lopinavir / ritonavir-based combined antiretroviral therapy (cART) for HIV-1 infection: A systematic review and meta-analysis
BACKGROUND: This systematic review and meta-analysis was conducted to evaluate the safety and effectiveness of Atazanavir/ritonavir over lopinavir/ritonavir in human immunodeficiency virus-1 (HIV-1) infection. METHODS: Clinical trials with a head-to-head...
Change in condom use in populations newly aware of HIV diagnosis in the United States and Canada: A systematic review and meta-analysis
HIV-infected individuals “aware” of their infection are more likely to use condoms, compared to HIV-infected “unaware” persons. To quantify this likelihood, we undertook a systematic review and meta-analysis of U.S....
