Category Archives: Prevention, Engagement and Care Cascade

Background: Pre-exposure prophylaxis, or PrEP, has been shown to be effective at reducing the risk of HIV infection, yet persons at-risk for acquiring HIV exhibit suboptimal uptake of and adherence...

BACKGROUND: In the era of eHealth, eHealth literacy is emerging as a key concept to promote self-management of chronic conditions such as HIV. However, there is a paucity of research...

This meta-analytic review synthesizes the findings of published independent studies that assessed the effectiveness of HIV prevention interventions in promoting condom usage in Asia. We focused on 20 studies that...

Key take-home messages There is no one-size-fits-all cost-effective HIV strategy. An intervention that is found to be effective at preventing HIV infection has a good chance of being cost-effective due...

Key take-home messages The Canadian literature primarily encompasses female sex workers in Vancouver, and studies from other high income countries often addressed demographic niches that were not transferrable to the...

Key tale-home messages Interventions that make use of motivational interviewing can be effective in changing risk behaviours for people living with HIV; the longer the motivational interviewing intervention, the more...

Key take-home messages Men who have sex with men are two to four times more likely than men in the general population to have experienced childhood sexual abuse. Men who...

BACKGROUND: Knowledge and uptake of high-efficacy HIV prevention strategies such as pre-exposure prophylaxis (PrEP) and treatment as prevention (TasP) remain low among men who have sex with men (MSM) who...

BACKGROUND: Currently, there is no consensus on the efficacy and safety of lamivudine (LAM) plus tenofovir disoproxil fumarate (TDF) combination therapy versus lamivudine monotherapy in HBV/HIV coinfected patients. METHODS: A...

Background: Dual therapy (DT) with a ritonavir-boosted PI (PI/r) plus lamivudine has proven non-inferior (12% margin) to triple therapy (TT) with PI/r plus two nucleos(t)ide reverse transcriptase inhibitors [N(t)RTIs] in...

OBJECTIVE: We evaluated the effectiveness of interventions aimed at improving antiretroviral therapy (ART) adherence during pregnancy in sub-Saharan Africa. METHODS: For this meta-analysis, the following databases were searched: MEDLINE Complete,...

BACKGROUND: Nearly all newly infected children acquire Human Immunodeficiency virus (HIV) via mother-to-child transmission (MTCT) during pregnancy, labour or breastfeeding from untreated HIV-positive mothers. Antiretroviral therapy (ART) is the standard...