Category Archives: Prevention, Engagement and Care Cascade
The efficacy of motivational interviewing: A meta-analysis of controlled clinical trials
A meta-analysis was conducted on controlled clinical trials investigating adaptations of motivational interviewing (AMIs), a promising approach to treating problem behaviors. AMIs were equivalent to other active treatments and yielded...
Diarrhea associated with lopinavir/ritonavir-based therapy: Results of a meta-analysis of 1469 HIV-1-infected participants
BACKGROUND: Antiretroviral therapy is associated with adverse events (AEs). The most frequently reported AE associated with lopinavir/ritonavir (LPV/r) containing regimens is diarrhea. The objective of this meta-analysis is to describe...
Efficacy and cost-effectiveness of the first generation of HIV prevention interventions for people with severe and persistent mental illness
BACKGROUND: People with serious mental illness are at elevated risk for human immunodeficiency virus (HIV) infection. A small body of published research has evaluated the efficacy of HIV prevention interventions...
Vitamin supplementation for prevention of mother-to-child transmission of HIV and pre-term delivery: A systematic review of randomized trial including more than 2800 women
Background: Observational studies have suggested that low serum vitamin levels are associated with increased mother-to-child transmission (MTCT) of HIV and increased preterm delivery. We aimed to determine the efficacy of...
Behavioral interventions to reduce incidence of HIV, STD, and pregnancy among adolescents: A decade in review
PURPOSE: To review adolescent sexual risk-reduction programs that were evaluated using quasi-experimental or experimental methods and published in the 1990s. We describe evaluated programs and identify program and evaluation issues...
Protease inhibitor-containing antiretroviral treatment and tuberculosis: Can rifabutin fill the breach?
OBJECTIVE: To assess how to best manage co-administration of rifabutin (RFB) and human immunodeficiency virus 1 (HIV-1) protease inhibitor (PI) containing antiretroviral treatment (ART). Recommended for initial anti-tuberculosis treatment, rifampicin...
Interactions between protease inhibitors and acid-reducing agents: A systematic review
OBJECTIVE: The purpose of this article is to provide a systematic review of the available pharmacokinetic and clinical data on drug interactions between protease inhibitors (PIs) and acid-reducing agents, and...
A systematic review of school-based sexual health interventions to prevent STI/HIV in sub-Saharan Africa
BACKGROUND: The HIV/AIDS epidemic remains of global significance and there is a need to target (a) the adolescent age-groups in which most new infections occur; and (b) sub-Saharan Africa where...
Immune reconstitution inflammatory syndrome in patients starting antiretroviral therapy for HIV infection: A systematic review and meta-analysis
In patients with HIV-1 infection who are starting combination antiretroviral therapy (ART), the incidence of immune reconstitution inflammatory syndrome (IRIS) is not well defined. We did a meta-analysis to establish...
Barriers to access to antiretroviral treatment in developing countries: A review
OBJECTIVE: To present a review of barriers impeding people living with HIV/AIDS in developing countries from accessing treatment, and to make recommendations for further studies. METHODS: Electronic databases, websites of...
