Category Archives: Prevention, Engagement and Care Cascade
The effectiveness of opioid maintenance treatment in prison settings: A systematic review
AIMS: To review evidence on the effectiveness of opioid maintenance treatment (OMT) in prison and post-release. METHODS: Systematic review of experimental and observational studies of prisoners receiving OMT regarding treatment...
Comparative efficacy of Lamivudine and emtricitabine: A systematic review and meta-analysis of randomized trials
INTRODUCTION: Lamivudine and emtricitabine are considered equivalent by several guidelines, but evidence of comparable efficacy is conflicting. METHODS: We searched two databases up to June 30 2013 to identify randomized...
Efficacy of peer-led interventions to reduce unprotected anal intercourse among men who have sex with men: A meta-analysis.
OBJECTIVE: To conduct a systematic review and meta-analysis to evaluate the efficacy of peer-led interventions in reducing unprotected anal intercourse (UAI) among men who have sex with men (MSM). METHODS:...
Complementary and alternative medicine use among HIV-positive people: Research synthesis and implications for HIV care
Use of complementary and alternative medicine (CAM) is prevalent among HIV-positive individuals despite the success of antiretroviral treatments and limited evidence of CAM’s safety and efficacy. To characterize the potential...
Emergence of drug resistance in HIV type 1-infected patients after receipt of first-line highly active antiretroviral therapy: A systematic review of clinical trials
Background. Resistance to antiretroviral combination therapy is associated with increased mortality. Understanding the relative risks of emerging resistance to first-line therapy is of importance for both resource-rich and resource-poor settings....
Standard care quality determines treatment outcomes in control groups of HAART-adherence intervention studies: Implications for the interpretation and comparison of intervention effects.
Objective: Clinical trials of behavioral interventions seek to enhance evidence-based health care. However, in case the quality of standard care provided to control conditions varies between studies and affects outcomes,...
Co-formulated abacavir-lamivudine-zidovudine for initial treatment of HIV infection and AIDS
Background: UNAIDS estimates that 34 million people are currently living with the human immunodeficiency virus (HIV) worldwide. Currently recommended regimens for initiating HIV treatment consist of either a non-nucleoside reverse...
A systematic review of antiretroviral adherence interventions for HIV-infected people who use drugs
HIV-infected persons who use drugs (PWUDs) are particularly vulnerable for suboptimal combination antiretroviral therapy (cART) adherence. A systematic review of interventions to improve cART adherence and virologic outcomes among HIV-infected...
HIV prevalence among female sex workers, drug users and men who have sex with men in Brazil: A systematic review and meta-analysis
BACKGROUND:The Brazilian response towards AIDS epidemic is well known, but the absence of a systematic review of vulnerable populations – men who have sex with men (MSM), female sex workers...
A decade in review: Building on the experiences of past adolescent STI/HIV interventions to optimise future prevention efforts
The major purpose of this article is to systematically review and synthesise empirical findings from selected adolescent STI/HIV interventions conducted in the United States between 1994 and 2004. Specifically, the...
