Category Archives: Prevention, Engagement and Care Cascade
Efficacy of antiretroviral drugs in reducing mother-to-child transmission of HIV in Africa: A meta-analysis of published clinical trials
Antiretroviral drugs (ARVs) have been shown to be efficacious in decreasing mother-to-child transmission (MTCT) of HIV. A summary estimate of the efficacy of ARVs in reducing MTCT is important for...
Promoting HIV and sexual safety behaviour in people with severe mental illness: A systematic review of behavioural interventions
People diagnosed with severe mental illness (SMI) are at greater risk of HIV than the general population. However, little attention has been given to how best to reduce sexual risk...
Boosted protease inhibitors as a therapeutic option in the treatment of HIV-infected children
OBJECTIVE: Paediatric HIV treatment must address various special considerations. Administration of pharmacokinetically enhanced protease inhibitors (PIs) can improve paediatric therapeutic outcomes. The objective of this study was to review the...
School based sex education and HIV prevention in low- and middle-income countries: A systematic review and meta-analysis
OBJECTIVES: School-based sex education is a cornerstone of HIV prevention for adolescents who continue to bear a disproportionally high HIV burden globally. We systematically reviewed and meta-analyzed the existing evidence...
Effect of cotrimoxazole on mortality in HIV-infected adults on antiretroviral therapy: A systematic review and meta-analysis
OBJECTIVE: To determine whether cotrimoxazole reduces mortality in adults receiving antiretroviral therapy (ART) for human immunodeficiency virus (HIV) infection in low- and middle-income countries through a systematic review and meta-analysis....
Effective approaches to reducing adolescent unprotected sex, pregnancy, and childbearing
In the United States, there exist a multitude of different approaches to reducing adolescent sexual risk-taking, unintended pregnancy, childbearing, and sexually transmitted disease, including HIV. While many of these approaches...
A systematic review of the use of atazanavir in women infected with HIV-1
BACKGROUND: Despite increasing numbers of women with HIV worldwide, females are under-represented in clinical trials of antiretrovirals and literature addressing gender differences in clinical outcomes, treatment discontinuation, adverse events and...
A systematic review of HIV/AIDS survival and delayed diagnosis among Hispanics in the United States
HIV/AIDS disproportionately affects Hispanics. Our objective was to determine the risk of late diagnosis and rate of survival after HIV/AIDS diagnosis among Hispanics compared to other racial/ethnic groups. We performed...
