Category Archives: Prevention, Engagement and Care Cascade

Effects of economic interventions on pediatric and adolescent HIV care outcomes: A systematic review

2023

Economic insecurity and poverty present major barriers to HIV care for young people. We conducted a systematic review of the current evidence for the effect of economic interventions on HIV...

Prevalence and trends of advanced HIV disease among antiretroviral therapy-naive and antiretroviral therapy-experienced patients in South Africa between 2010-2021: A systematic review and meta-analysis

2023

BACKGROUND: Despite the significant progress made in South Africa in getting millions of individuals living with HIV into care, many patients still present or re-enter care with Advanced HIV Disease...

Current ARTs, virologic failure, and implications for AIDS management: A systematic review

2023

Antiretroviral therapies (ARTs) have revolutionized the management of human immunodeficiency virus (HIV) infection, significantly improved patient outcomes, and reduced the mortality rate and incidence of acquired immunodeficiency syndrome (AIDS). However,...

Attrition one year after starting antiretroviral therapy before and after the programmatic implementation of HIV “Treat All” in Sub-Saharan Africa: A systematic review and meta-analysis

2023

Introduction Evidence on the real-world effects of “Treat All” on attrition has not been systematically reviewed. We aimed to review existing literature to compare attrition 12 months after antiretroviral therapy (ART)...

Provision of HIV prevention and care services to farmworkers in sub-Saharan African countries

2023

OBJECTIVES: To summarise data on human immunodeficiency virus (HIV) services available to farmworkers in sub-Saharan Africa (SSA). METHODS: We conducted a systematic review to understand which HIV prevention and care...

Impact of differentiated service delivery models on retention in HIV care and viral suppression among people living with HIV in sub-Saharan Africa: A systematic review and meta-analysis of randomised controlled trials

2023

Differentiated service delivery (DSD) models, such as adherence clubs (ACs), are client-centred approaches where clinically stable people living with HIV (PLHIV) meet to receive various services, including psychosocial support, brief...

The efficacy and tolerability of latency-reversing agents in reactivating the HIV-1 reservoir in clinical studies: A systematic review

2023

INTRODUCTION: Understanding the clinical potency of latency-reversing agents (LRAs) on the HIV-1 reservoir is useful to deploy future strategies. This systematic review evaluated the effects of LRAs in human intervention...

Effectiveness of linkae to care and prevention interventions following HIV self-testing: A global systematic review and meta-analysis

2023

Over 38.4 million people were living with HIV globally in 2021. The HIV continuum includes HIV testing, diagnosis, linkage to combined antiretroviral therapy (cART), and retention in care. An important...

The success of serious game and gamified systems in HIV prevention and care: Scoping review

2023

BACKGROUND: AIDS, which is caused by HIV, has long been one of the most significant global public health issues. Since the beginning of the HIV epidemic, various types of nonelectronic...

HIV stigma reduction interventions among health care providers and students in different countries: A systematic review

2023

BACKGROUND: Health care providers’ stigmatizing attitudes are obstacles to patients’ well-being and quality of life. Dealing with HIV-related stigma and understanding the impact of feasible interventions on reducing stigmatizing attitudes...

A review of bidimensional acculturation and STI/HIV-related sexual risk behaviours among Hispanic youth

2023

A growing body of research suggests that acculturation may play a role in the disproportionate likelihood of sexual risk behaviour and STI/HIV infection among Hispanic youth in the USA. We...

Barriers and facilitators to acceptability and uptake of pre-exposure prophylaxis (PrEP) among Black women in the United States: A systematic review

2023

OBJECTIVES: Pre-exposure prophylaxis (PrEP) provides a salient avenue to address the profound HIV-related health disparities that Black women in the United States face. This systematic review assessed the acceptability of...

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